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The importance of BCR-ABL kinase domain
mutation analysis in CML

Susan Branford, University of Adelaide, Australia

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vep branford mutationanalysis

 

Issues covered

  • Mutations as a mechanism of imatinib resistance
  • Why mutations arise
  • When to test for mutations
  • Therapeutic options in the presence of mutations

 

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Facteur de variabilité de la réponse au ITK</li>
              <li>Les trois grand mécanismes de résistance</li>
              <li>La réponse au traitement</li>
              <li>Autres inhibiteurs de tyrosine kinase: le Nilotinib et le Dasatinib