iCMLf Knowledge Centre

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iCMLf Knowledge Center


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View new presentations on the Virtual Education Program

July 2016 - Three new online presentations have recently been added to the Virtual Education Program. Again we were able to engage leaders in the field of CML toVEP Mahon talk about the latest scientific findings on the management of CML. View the following new presentations featuring:

  • Stopping TKI therapy in Chronic Myeloid Leukemia
    Francois-Xavier Mahon, Hospital University of Bordeaux, France
  • Treating pediatric Chronic Myeloid Leukemia – an update
    Meinolf Suttorp, University Hospital Dresden, Germany
  • Perspectives on CML in the Emerging Regions (Interview)
    Pat Garcia-Gonzalez, CEO of The MAX Foundation and recipient of the inaugural iCMLf Prize

You can access the new presentations here

June 2016 issue of the iCMLf NewsletteriCMLf Newsletter June 16  
- now available 

Download the pdf file here

June 2016 - contents overview:

  • iCMLf Clinical Preceptorship Program - offering long-lasting benefits
  • New iCMLf educational news services - covering the latest advances in CML
  • CML story published in Blood - CML treatment-free remission critieria outlined
  • iCMLf Prizes - recognising outstanding contributions to CML management
  • iCMLf John Goldman Fund - supporting young physicians from the emerging regions
  • Upcoming important scientific meeting


iCMLf Diagnosis and Testing ProgramFirstTest

Apply now for 2016 grants

May 2016 - The iCMLf Diagnosis and Testing Program offers seeding grants to hematology institutions in emerging economic regions. The aim of the program is to facilitate the diagnosis, testing and long-term disease monitoring of CML patients in emerging economic regions where it is either limited, or not currently available.

Over 4 years the iCMLf have awarded 32 grants to enable CML diagnostics to be expanded and enhanced at a local level. This gives both physicians and patients the knowledge to make meaningful decisions on treatment. In 2016 the Foundation will offer 10 grants with funding of up to $10,000.

Applications will close on the 15th of July 2016. Expressions of interest are welcome to melissa@cml-foundation.org or read more for further information on how to apply.

Read more ...

2016 iCMLf Prize winner - Associate Professor Susan Branfordsusan branford

April 2016 - The iCMLf has awarded the 2016 iCMLf prize to Associate Professor Susan Branford. This award recognises the critically important work she has performed to improve the quality and availability of reliable molecular testing for CML in the emerging regions. Her efforts have significantly impacted and improved the management of so many CML patients in these regions.

The iCMLf Prize is awarded annually by the iCMLf to recognise outstanding contributions to the improvement of CML treatment in the emerging economic regions. The iCMLf Prize was formally named the ERSAP (Emerging Regions Support and Partnership Prize) and was first awarded in 2015 to Pat Garcia-Gonzalez, CEO of The Max Foundation.

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New monthly iCMLf news service available -05 medwireNews2
Latest advances from key CML publications

April 2016 - We are delighted to announce that from April we will be bringing you a monthly news service covering the latest clinical and scientific advances in CML.

The news service, provided by medwireNews Springer Healthcare’s independent news bureau, will include summaries of key CML publications. The CML stories are based on articles published in international peer-reviewed journals, or conference sessions and written by highly experienced and knowledgeable writers. 

With this independent educational service we continue to expand our online educational platform complementing other services such as the Virtual Education Program or the Case Discussion Forum. Our aim is to grant equal access to CML education in all parts of the world for the purpose of best possible care for all CML patients.

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The 2016 iCMLf Rowley Prize is awarded to Professors Groffen and HeisterkampNora HeisterkampJohn Groffen

March 2016 - In 2016 the iCMLf Directors and a panel of previous prize winners, have named two renowned scientists as the recipients of the 2016 Rowley Prize: Professor John Groffen and Professor Nora Heisterkamp. This prestigious award celebrates the people who have made outstanding lifetime contributions to the understanding of the biology of CML.

Dr Groffen and Dr Heisterkamp are recognised as co-discoverers of the genes that are directly involved in the t(9;22) Philadelphia (Ph) translocation found in chronic myeloid leukemia (CML). They localized the human c-ABL gene on chromosome 9 and molecularly cloned and mapped the gene. By isolation of breakpoint fragments, they showed that the ABL gene becomes fused to sequences on the Ph-chromosome in CML. They molecularly cloned this region on chromosome 22 and named it the “breakpoint cluster region" (BCR) gene. Further studies with null mutant bcr mice were undertaken to elucidate the normal cellular function of Bcr.

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