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Meeting hall

Top scoring abstracts: Biology and Clinical 2020

View best awarded abstract presentations from the 22nd John Goldman E-Conference on CML

  • Best awarded clinical abstract 2020: Professor Susan Branford
    Targeted RNA-based gene sequencing identifies mutated blood cancer-linked genes at diagnosis of CML that are associated with treatment failure
  • Best awarded biology abstract 2020: Dr Bac Viet Le
    Tgfßr - SMAD3 signaling protects CML and other myeloid malignancies from synthetic lethality triggered by PARP inhibited bone marrow mircroenvironment

Keynote presentations from the recipients of the 2020 iCMLf Prizes

At the 22nd John Goldman E-Conference on CML the 2020 iCMLf prize winners have been awarded their prizes. During keynote presentations the prize recipients shared personal perspectives on their scientific and clinical work for CML over the past years. You can view web streams of the Rowley Prize, the Goldman Prize and the iCMLf Prize keynote presentations here.

Collage 2020 Prize winners

 

  • 2020 Rowley Prize: Professor Ravi Bhatia
  • 2020 Goldman Prize: Professor Jane Apperley
  • 2020 iCMLf Prize: Dr Sabira Kurtovic

 

 

Keynote presentations from the recipients of the 2019 iCMLf Prizes

At the 21th Annual John Goldman Conference on CML in Bordeaux the iCMLf Directors awarded the Foundation’s 2019 prize medals. This was followed by keynote presentations from the three prize winners. You can view web streams of the Rowley Prize and the iCMLf Prize keynote presentations here. Unfortunately François-Xavier Mahon's presentation on 'Curing CML: To be, or not to be, that is the question' (Goldman Prize) is not available as a web stream.

Collage 2019 iCMLf Prizes

 

  • 2019 Rowley Prize: Professor Michael Deininger
  • 2019 Goldman Prize: Professor François-Xavier Mahon
  • 2019 iCMLf Prize: Dr Carolina Pavlovsky

 

 

Perspectives on the scientific aspects of the meeting from Professor Daniela Krause
Georg-Speyer Haus
University of Frankfurt (Germany) 

  • Concept of treatment-free remission
    • Immunological surveillance after treatment discontinuation
    • Analysis of different immune subsets 
    • A mathematical model for prediction of good response
  • Results from the workshop on metabolism 
  • The role of inflammation in CML
  • Aging - mutations that occur with aging
  • Therapy resistance
  • Stem cells and microenvironment
  • Existence of BCR-ABL independent mutations
  • Immunotherapy - resistance to CAR-T cells

 We apologize for the background noise in this video.

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Highlights from the John Goldman Conference on CML 2019:
CML experts give their personal perspectives

Perspectives on the clinical aspects of the meeting from Professor Jorge Cortes
Georgia Cancer Center
Augusta University, Augusta (USA)

  • Treatment-free remission as a new goal for patients with CML
    • Long-term follow-up data from the STIM study
    • Treatment strategies for patients with early and late relapse 
    • Biomarkers to predict a higher probability of relapse
    • Pharmacoeconomics of treatment discontinuation
  • Complex genetics of CML - the work of the Genomics Alliance
  • Clinical trial updates
    • SPIRIT trial
    • BEYOND study
    • Asciminib combinations
  • Fatigue during TKI therapy

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Highlights from the John Goldman Conference on CML 2018:
CML experts give their personal perspectives

In Spanish:
Perspectivas sobre los estudios de discontinuación de terapia que se mostraron
Dr Carolina Pavlovsky
FUNDALEU - Fundación para combatir la leucemia
Buenos Aires - Argentina

  • Resumen de los estudios de discontinuacíon de terapia más importantes, que incluyen
    • ENESTFreedom
    • ENESTStop
    • DASFree
  • Análisis de los estudios actuales sobre biomarcadores y otros factores predictivos que pueden predecir el éxito terapéutico y que pueden mostrar qué mutaciones pueden ser relevantes en pacientes resistentes