CML Publications

To keep you up-to-date on the latest scientific findings and on the clinical management of CML the iCMLf is pleased to present to you monthly updates from key CML publications in peer-reviewed journals. 

The iCMLf 'Publications of the month' are brought to you by Professor Timothy Hughes . From the many papers on CML published this month Professor Hughes has selected topical, interesting papers for your perusal including interesting articles from the emerging economic regions and recent papers on CML and COVID-19.

Read Professor Hughes' CML publications of the month: August 2020

Clinical publications

• A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukemia
  Smith G et al. Br J Haematol, July 2020 (epub ahead of print)
  – open access publication
• Moving on from 2013 to 2020 European LeukemiaNet recommendations for treating chronic myeloid leukemia: what has changed over the 7 years?
  Yilmaz U & Eskazan AE. Expert Rev Hematol, August 2020 (epub ahead of print)
  - open access publication
• A phase 1 study to evaluate the feasibility and efficacy of the addition of ropeginterferon alpha-2b to imatinib in patients with chronic phase chronic myeloid leukemia (CML) not achieving a deep molecular response (molecular remission 4.5) – AGMT-CML1
  Heibl S et al. Hematol Oncol, August 2020 (epub ahead of print)
• Treatment-free remission in chronic myeloid leukemia: the patient perspective and areas of unmet needs
  Sharf G et al. Leukemia, August 2020 – open access publication

Scientific publications

• RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses
  Adnan Awad S et al. Leukemia, August 2020 (epub ahead of print)
  – open access publication
• Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML
  Toda J et al. Oncogene, August 2020 – open access publication

Pediatric publications

• Lymphoblastic predominance of blastic phase in children with chronic myeloid leukemia treated with imatinib: A report from the I-CML-Ped Study
  Meyran D et al. Eur J Cancer, August 2020 (epub ahead of print)
• Sustained molecular response following a failed attempt of tyrosine kinase inhibitor discontinuation and the effects on growth in a child with CML: not always a short story
  Triche L et al. Pediatr Hematol Oncol, August 2020

ERSAP publications

• Early molecular response in East African Philadelphia chromosome-positive chronic myeloid leukemia patients treated with imatinib and barriers to access treatment
  Henke O et al. ecancer, August 2020 – open access publication

COVID-19 publications

COVID-19 and CML:

• SARS CoV2 infection in chronic myelogenous leukemia: Severe haematological presentation
  Sorà F et al. Transfus Apher Sci, July 2020 (epub ahead of print)
  – open access publication

COVID-19 and haematological malignancies/cancer:

• Clinical characteristics and risk factors associated with COVID-10 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study
  Passamonti F et al. Lancet Haematol, August 2020 (epub ahead of print)
  – open access publication
• Clinical characteristics, therapeutic management, and prognostic factors of adult COVID-10 inpatients with haematological malignancies
  Wu Y et al. Leuk Lymphoma, August 2020 (epub ahead of print)
• High-mortality rate in cancer patients with symptoms of COVID-10 with or without detectable SARS-CoV-1 on RT-PCR
  Assaad S et al. Eur J Cancer, August 2020 – open access publication