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Virtual Education

EHA 2019: NGS in CML - new standard diagnostic procedure? (Susan Branford)

EHA 2019 Branford

NGS in CML - New Standard Diagnostic Procedure?
Associate Professor Susan Branford, Centre for Cancer Biology Adelaide, Australia 

  • CML is a genetically uniform disease: BCR-ABL1
  • Catalogue of somatic mutations in cancer: COSMIC
  • Sanger sequencing is impractical for broad discovery
  • Association of mutated cancer genes and transformation
  • New therapies for BC based on mutation profile
  • Other genes not listed in the cancer gene census?
  • Multiple genomic events may impact outcome

This talk was first presented during the Education Session on Chronic Myeloid Leukemia at EHA. You will find more education materials from EHA at the EHA Learning Centre.