Mutation Screening:
What is standard of care today and the role of new modalities
Simona Soverini, University of Bologna, Italy 

• BCR-ABL kinase domain (KD) mutation for optimal patient management
• When to perform BCR-ABL KD mutation analysis
• How to perform BCR-ABL KD mutation analysis
• BCR-ABL KD mutation screening: key issues
• Next-generation sequencing (NGS): applications
• NGS for routine BCR-ABL mutatation testing: when?
• NGS for routine BCR-ABL mutation screening: hurdles
• Conclusions