Archive: CML Publications
2026 Clinical Papers
July
Introduction to the review series. Chronic myeloid leukemia in 2026
Radich J. Haematologica, July 2026
open access publication
Favorable tolerability of Asciminib versus ATP-competitive tyrosine kinase inhibitors in the ASC4FIRST study of newly diagnosed patients with chronic-phase chronic myeloid leukemia
Issa GC et al. Haematologica, July 2026 (epub ahead of print)
open access publication
Asciminib monotherapy in patients with BCR::ABL1 T315I-mutated chronic-phase chronic myeloid leukemia: phase 1 trial final results
Cortes JE et al. Leukemia, July 2026 (epub ahead of print)
open access publication
Five-year follow-up of OPTIC: long-term efficacy, safety, and mutation analyses of ponatinib in chronic-phase chronic myeloid leukemia from a randomized phase 2 trial
Kantarjian H et al. Leukemia, July 2026 (epub ahead of print)
open access publication
Diabetic patients with newly diagnosed chronic myeloid leukemia: TKI choice and early adverse events. A real-life survey with the Italian CML Network
Russo S et al. Eur J Haematol, July 2026 (epub ahead of print)
Development and external validation of a transcriptome-based multivariable prediction model for treatment-free remission in chronic myeloid leukemia
Alcazer V et al. J Clin Oncol, July 2026
Reattempt of tyrosine kinase inhibitor discontinuation after maintenance therapy with ponatinib in patients with chronic myeloid leukemia in the chronic-phase: Results of the Japan Adult Leukemia Study Group RE-STOP219 Study
Iriyama N et al. Br J Haematol, July 2026 (epub ahead of print)
open access publication
Olverembatinib: real progress in BCR::ABL1 leukemia?
Oehler VG et al. Haematologica, July 2026 (epub ahead of print)
open access publication
Frontline nilotinib versus dasatinib in newly diagnosed chronic phase chronic myeloid leukemia: A propensity score analysis based on Agenzia Italiana del Formaco Monitoring Registries
Breccia M et al. Clin Lymphoma Myeloma Leuk, July 2026
Ponatinib safety profile: An analysis of 10 years of real-world experience
Jabbour E et al. Drug Saf, July 2026 (epub ahead of print)
open access publication
Dynamic improvement of the treatment-free remission prognostic score by prolonging MR4 duration in chronic myeloid leukemia
Fujita M and Ureshino H. Br J Haematol, July 2026
Real-world evidence-based study on treatment-free remission in chronic myeloid leukemia
Cheng F et al. J Natl. Compr Canc Netw, July 2026 (epub ahead of print)
open access publication
June
Second-line bosutinib for chronic phase chronic myeloid leukemia after imatinib: final, 10-year results of a phase I/II study
Gambacorti-Passerini C et al. Haematologica, June 2026 (epub ahead of print)
– open access publication
Longitudinal changes in body weight and body mass index in patients with chronic-phase chronic myeloid leukemia with tyrosine kinase inhibitors: A retrospective observational study
Alshurafa A et al. Oncology, June 2026 (epub ahead of print) – open access publication
Asciminib provides better efficacy and favorable safety and tolerability profile against investigator-selected tyrosine kinase inhibitors in East Asian patients with newly diagnosed chronic myeloid leukemia: Results from a subgroup analysis of the pivotal ASC4FIRST Study
Takahashi N et al. Cancer Med, June 2026 – open access publication
What is the optimal threshold for aberrant lymphoblasts at diagnosis to predict lymphoid transformation in chronic myeloid leukemia?
Jiang Z et al. Cytometry B Clin Cytom, June 2026 (epub ahead of print)
A survey on the management of chronic myeloid leukemia in chronic phase from the perspectives of both patients and physicians
Eşkazan AE et al. Ann Hematol, June 2026 (epub ahead of print)
Impact of somatic mutations on treatment response and resistance in chronic myeloid leukemia
Mishra S et al. Int J Hematol, June 2026 (epub ahead of print)
Comprehensive molecular characterization of treatment-free remission and molecular relapse in chronic myeloid leukemia patients: the EURO-SKI Biomarker Study
Rinaldetti S et al. Leukemia, June 2026 (epub ahead of print) – open access publication
Treatment-free remission and immune profiling after frontline second-generation TKI therapy in CML
Takahashi N et al. Blood Adv, June 2026 (epub ahead of print)
Early predictors of MR4.5 attainment and eligibility after TKI discontinuation in CML treated with second-generation TKIs
Ono T et al. Blood Adv, June 2026 (epub ahead of print)
Response-adapted dasatinib de-escalation strategy compared to upfront low-dose dasatinib: A prospective cohort study
Halder R et al. Leuk Res, June 2026
May
From fatal disease to functional cure: 25 years of tyrosine kinase inhibition in chronic myeloid leukemia
Hochhaus A et al. Leukemia, May 2026
(epub ahead of print) – open access publication
2001-2026: LEUKEMIA celebrates 25 years of tyrosine kinase inhibitors
Gale RP and Hochhaus A. Leukemia, May 2026
(epub ahead of print)
The adverse prognostic impact of HMGCLL1 gene variants can be abrogated by frontline second-generation tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
Perusini MA et al. Leukemia, May 2026
Identification of predictive biomarkers based on cytokine profile for molecular relapse after treatment-free remission in chronic myeloid leukemia patients
Vasconcelos Cordoba B et al. Cells, April 2026 – open access publication
Final results of nilotinib versus nilotinib combined with pegylated interferon alfa-2a as first-line therapy in chronic-phase chronic myeloid leukemia in France (PETALs): an open-label, multicentre, randomized phase 3 trial
Nicolini FE et al. Lancet Haematol, May 2026
Olverembatinib-based therapy in patients with transformed chronic myeloid leukemia in lymphoid blast phase or relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia: A multicentre retrospective study
Bao M et al. Clin Lymphoma Myeloma Leuk, May 2026
Effects of a high-fat meal on the pharmacokinetics of Olverembatinib in patients with chronic myeloid leukemia
Wang H et al. Clin Transl Sci, May 2026 – open access publication
Real-world outcomes of ponatinib in heavily pretreated patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia
Lee S et al. Ann Hematol, May 2026 (epub ahead of print)
Assessment of transitioning from high-potency to low-potency inhibitors in chronic myeloid leukemia (CML) patients: The downgrading-imact (D-IMPACT) project
Abruzzese E et al. Cancers(Basel), May 2026 – open access publication
Long-term safety and efficacy of ponatinib in intolerant chronic myeloid leukemia: Subanalysis of the observational study of Iclusig (ponatinib) treatment in patients with chronic myeloid leukemia in Italy
Breccia M et al. Haematologica, May 2026 (epub ahead of print) – open access publication
BCR-ABL1 transcript ≤10% IS an early molecular response predictor of treatment-free remission eligibility in chronic myeloid leukemia
Rasekh EO et al. Clin Lymphoma Myeloma Leuk, April 2026 (epub ahead of print)
April
Management of tyrosine kinase inhibitors and donor lymphocyte infusions post transplantation for chronic myeloid leukemia: a survey of contemporary practice on behalf of the chronic malignancies working party of EBMT
Kanellopoulos A et al. Bone Marrow Transplant, April 2026 (epub ahead of print)
ASC4OPT: asciminib treatment optimization study in patients with chronic myeloid leukemia in chronic phase previously treated with two or more tyrosine kinase inhibitors
Hochhaus A et al. Leukemia, April 2026 – open access publication
Age and gender effects on molecular responses in chronic myeloid leukemia patients by first-line treatment: an Italian CML network cohort study
Breccia M et al. Ann Hematol, April 2026 – open access publication
A current overview of quality of life research in chronic myeloid leukemia (CML)
Deneberg S et al. Cancers (Basel), April 2026 – open access publication
Evolution of the European LeukemiaNet recommendations for chronic myeloid leukemia
Yolcu A and Haznedaroglu IC. Expert Rev Hematol, April 2026 (epub ahead of print)
The care and cure of the leukemias in 2026
Kantarjian H et al. Am J Hematol, April 2026
Patients’ and healthcare providers’ views regarding dose reduction of tyrosine kinase inhibitors in chronic myeloid leukemia: a qualitative study
Lokhorst DN et al. Oncologist, April 2026 – open access publication
A Novel CIP2A and BCL-XL Clinical Diagnostic Toolkit to Predict Disease Progression and Treatment-Free Remission in Chronic Myeloid Leukaemia
Basabrain, A.A.et al. Int. J Mol Sci, March 2026
Myeloproliferative neoplasms with concomitant chronic myeloid leukemia are associated with TKI resistance and poor outcomes
Gagnon, L.L. et al. Leukemia, March 2026 – open access publication
March
Asciminib demonstrates superior efficacy and safety in newly diagnosed chronic myeloid leukemia in the ASC4FIRST trial
Cortes JE et al. Blood, March 2026
open access publication
Imatinib outcomes in chronic myeloid leukemia across diverse healthcare settings: A systematic review and meta-analysis
Miranda-Galvis M et al. Blood Cancer J, March 2026
open access publication
Introducing a prognostic score for successful treatment-free remission in chronic myeloid leukemia
Claudiani S et al. Br J Haematol, March 2026 (epub ahead of print)
open access publication
Shared identity and patient care: adherence to guideline-recommended biomarker testing in chronic myeloid leukemia
Montano-Campos JF et al. J Natl Canc Netw, March 2026
open access publication
Predictive biomarkers of sustained treatment-free remission in chronic myeloid leukemia: gene expression analyses from the ENESTfreedom and ENESTop studies
Radich JP et al. Haematologica, March 2026 (epub ahead of print)
open access publication
Imatinib and nilotinib are equally successful in achieving treatment-free remission
Cheng F et al. Blood Cancer J, March 2026
open access publication
Tyrosine kinase inhibitors, chronic myeloid leukemia, and pregnancy: pharmacotherapeutic challenges and recommendations
Haddad FG et al. Expert Opin Pharmacother, March 2026 (epub ahead of print)
Management of chronic myeloid leukemia with tyrosine kinase inhibitors: adverse events, toxicities and therapy dosing
Oehler VG et al. Haematologica, March 2026 (epub ahead of print)
open access publication
Restless leg syndrome in chronic myeloid leukemia: an overlooked condition with a significant impact on health-related quality of life
Gürer T et al. Ann Hematol, March 2026
open access publication
Very long-term outcomes of chronic-phase chronic myeloid leukemia patients treated with imatinib: A 25-year real-world cohort study
Costa A et al. Br J Haematol, March 2026 (epub ahead of print)
Outcomes of patients treated with dasatinib 50 mg/d: A Pooled Analysis
Haddad FG et al. Clin Lymphoma Myeloma Leuk, March 2026 (epub ahead of print)
Five-year analysis of J-SKI: an observational study of TKI discontinuation in patients with CML in Japan
Takahashi N et al. Int J Hematol, March 2026 (epub ahead of print)
open access publication
Beyond ATP: asciminib and the allosteric path in CML
Abruzzese E et al. Blood, March 2026
ELN 2025 and somatic NGS in CML: a pragmatic framework for selective testing and interpretation beyond BCR::ABL1
Mishra S et al. Leuk Lymphoma, March 2026 (epub ahead of print)
February
Development of a prognostic scoring system for chronic myeloid leukemia in blast phase
Lauseker M et al. Leukemia, February 2026 (epub ahead of print)
open access publication
A plain language summary of how the body processes a lower-dose nilotinib tablet (DanzitenTM) compared with the existing capsule (Tasigna®)
Mauro M et al. Future Oncol, February 2026
Second attempt to discontinue TKI after molecular relapse in patients with chronic myeloid leukemia: A real-life Italian multicenter study
Iurlo A et al. Cancer, February 2026
open access publication
Extended long-term follow-up and the survival of Stop Imatinib Study
Mahon FX et al. Blood Neoplasia, February 2026
open access publication
Leveraging model-informed drug development to predict asciminib efficacy in second-line treatment of chronic myeloid leukemia in chronic phase
Sy SKB et al. Clin Pharmacokinet, February 2026 (epub ahead of print)
Pregnancy-related adverse events with tyrosine kinase inhibitor use in chronic myeloid leukemia: A FAERS Pharmacovigilance analysis (2001 – 2024)
Faisal MS et al. Clin Lymphoma Myeloma Leuk, February 2026
Efficacy and safety of 50 mg versus 100 mg daily frontline dasatinib therapy in chronic-phase chronic myeloid leukemia: a non-controlled, observational dose-comparable cohort study
Cheng F et al. BMC Cancer, February 2026 (epub ahead of print)
open access publication
Second- and third-generation BCR-ABL tyrosine kinase inhibitors and the risk of pulmonary arterial hypertension: A prevalent new-user design
Jambon-Barbara C et al. Circulation, February 2026 (epub ahead of print)
open access publication
A BCR::ABL1 exon 13 variant leads to systematic underestimation of transcript level in the molecular monitoring of CML
Boucher L et al. Leuk Res, February 2026 (epub ahead of print)
Evolving therapeutic algorithms in chronic myeloid leukemia: Integrating efficacy, safety, and survivorship
Leyfman Y et al. Biomedicines, February 2025
open access publication
The importance of bone marrow biopsy for chronic myeloid leukemia classification – a case report
Gonçalves NY et al. HJ Hematop, February 2026
open access publication
Should you be afraid of the big bad wolf? A practical real-world review for the comfortable use of bosutinib in the therapy of chronic myeloid leukemia
Lipton JH. J Cancer Immunol, December 2025
open access publication
Secondary chronic myeloid leukemia in the blast phase with mixed phenotype after radiation therapy: A Case Report
Aoki M et al. EJHaem, February 2026
open access publication
January
Randomized phase 3 trial of Ropeginterferon alpha-2b versus surveillance after tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia (ENDURE/CML-IX)
Burchert A et al. Leukemia, January 2026 (epub ahead of print)
open access publication
Risk factors and reasons for switching from front-line therapy in the Italian CML network: A cohort study
Breccia M et al. Br J Haematol, January 2026 (epub ahead of print)
Treatment-free remission after two nilotinib consolidation durations in chronic myeloid leukemia treated with imatinib: Phase 3 ENESTPath results
Réa D et al. Leukemia, January 2026 (epub ahead of print)
Management of chronic myeloid leukemia during pregnancy: Review of evidence and treatment algorithm
Haddad FG et al. Clin Lymphoma Myeloma Leuk, January 2026
Real-world outcomes with low-dose dasatinib (50 mg) in imatinib-resistant chronic myeloid leukemia chronic-phase: A retrospective analysis of efficacy and safety
Gangadaran N et al. Cancer Rep (Hobokken), January 2026
open access publication
Evaluating the safety of combining tyrosine kinase inhibitors with anticoagulants in chronic myeloid leukemia: A systematic review
Gameil A et al. Oncology, January 2026 (epub ahead of print)
open access publication
One-year consolidation with ponatinib 15 mg in chronic myeloid leukemia on deep molecular response with imatinib
Pérez-Lamas L et al. Ann Hematol, January 2026
open access publication
Prediction of relapse after discontinuation of tyrosine kinase inhibitor treatment in chronic myeloid leukemia
Ross DM. Leuk Lymphoma, January 2026 (epub ahead of print)
Introduction to a How I Treat series on chronic myeloid leukemia
Gotlib J. Blood January 2026
How I treat advanced phases of CML
Mauro MJ. Blood, January 2026
How I evaluate and treat resistance and relapse in CML
Soverini S and Castagnetti F. Blood, January 2026
How I individualize frontline treatment for chronic phase CML
Leyte-Vidal A and Shah NP. Blood, January 2026
How I approach hematopoietic stem cell transplantation for CML in a TKI world
Chalandon Y et al. Blood, January 2026
How I manage chronic myeloid leukemia during pregnancy
Abruzzese E, Chelysheva E. Blood January 2026
Advances of next-generation STAMP inhibitors in chronic myeloid leukemia
Costa A and Breccia M. Expert Opin Investig Drugs, January 2026
Drug resistance in chronic myeloid leukemia: The involvement of Galectin-1 and Galectin-3
Yildirim C. Mol Biol Rep, January 2026
Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow
Patterson SD et al. Leukemia, January 2026 (epub ahead of print)
open access publication
An overview of chronic myeloid leukemia treatment:
From tyrosine kinase inhibitors to novel and emerging therapies
Sekar AJ et al. Eur J Haematol, January 2026 (epub ahead of print)
open access publication
Influence of pharmacokinetics-related polymorphisms on asciminib exposure in patients with Japanese chronic myeloid leukemia
Takahashi N et al. Eur J Clin Pharmacol, January 2026
Specifically targeting the ABL myristoyl pocket: STAMP inhibitors for chronic myeloid leukemia
Ureshino H and Kimura S. Expert Rev Hematol, January 2026 (epub ahead of print)
2026 Scientific Papers
July
Improved inter-lab precision after CML international scale adaptation: a 15-year history of BCR::ABL1 proficiency testing
Kim AS et al. Leukemia, July 2026 (epub ahead of print)
open access publication
Development and validation of an in-house one-step RT-qPCR method for the quantification of the BCR::ABL1 p210 transcripts
Damerchiloo F et al. Sci Rep, July 2026 (epub ahead of print)
open access publication
Measurable residual disease and the unresolved biology of leukemic stem cells
Bhartiya D et al. Stem Cell Rev Rep, July 2026 (epub ahead of print)
Genetic Profile, Treatment Response, and Outcomes of BCR::ABL1-Positive Mixed-Phenotype Acute Leukemia: A Study From the BCR::ABL1 Pathology Group
Shen Q., et al. Modern Pathology, May 2026
open access publication
June
Direct measurement of in vivo BCR::ABL1 kinase inhibition reveals stronger potency of asciminib compared with imatinib and nilotinib
Kok CH et al. Leukemia, June 2026 (epub ahead of print) – open access publication
Multicolor detection of chronic myeloid leukemia stem cells, including novel marker CD69, predicts survival and early hematological toxicity
Culen M et al. Haematologica, June 2026 (epub ahead of print) – open access publication
Localization of p210 BCR-ABL to the mitochondria promotes chronic myeloid leukemia cell proliferation through cIAP signaling
Ikegami A et al. FASEB J, June 2026
Prolonged BCR::ABL1 induction in the SCL-tTA mouse recapitulates gene expression signatures and therapeutic vulnerabilities of primary imatinib-resistant chronic myeloid leukemia
Shyamsunder P et al. Leukemia, June 2026 (epub ahead of print)
May
BCR-ABL drives transcriptional reprogramming of chronic myeloid leukemia cells for immune evasion through C/EBPβ
Lu X et al. MedComm (2020), April 2026 eCollection May 2026 – open access publication
Circular RNA in chronic myeloid leukemia
(Commentary on Papaioannou D. et al Blood, May 2026)
Gambacorti-Passerini C. Blood, May 2026
circPCMTD1: a protein-coding circular RNA that regulates DNA damage response in BCR/ABL1-positive leukemias
Papaioannou D et al. Blood, May 2026
Cytogenetic diversity of variant Philadelphia translocations in chronic myeloid leukemia
Tokac AGB et al. Int J Lab Hematol, May 2026 (epub ahead of print)
– open access publication
CD56(+)/CD38(+) neutrophils: Rapid and specific flow cytometric signature for chronic myeloid leukemia
Laganà A et al. Mediterr J Hematol Infect Dis, May 2026 – open access publication
Cracking the CODEX of the leukemic BM microenvironment
(Commentary on Li L. et al Blood, May 2026)
Duarte D et al. Blood, May 2026
High-dimensional spatiotemporal single-cell atlas and 3D imaging of the bone marrow microenvironment during CML progression
Li L et al. Blood, May 2026
Reduced levels of ITGB1 cause activation of P38MAPK-ERK-LYN axis of BCR::ABL1 signaling despite inactivation of the oncoprotein by imatinib – novel resistance mechanism in blast crisis of chronic myeloid leukemia unraveled
Agrawal N et al. Cell Commun Signal, May 2026 (epub ahead of print)
– open access publication
April
Targeting the BCR::ABL1 kinase: Advances beyond imatinib in chronic myeloid leukemia
Naderi Z et al. Curr Hematol Malig Rep, April 2026
Targeting STAT5 via CRISP/Cas9 restores TKI sensitivity in resistant CML cells
Çelik B et al. Med Oncol, April 2026 – open access publication
Understanding drug resistance in chronic myeloid leukemia through the lens of leukemia stem cell states: insights from single-cell analyses
Krishnan V et al. Haematologica, April 2026 (epub ahead of print) – open access publication
An AI-enabled single-cell transcriptomic analysis pipeline for gene signature discovery in natural killer cells linked to remission outcomes in chronic myeloid leukemia
Borra S et al. Biology (Basel), April 2026 – open access publication
March
Chronic myeloid leukemia: have basophils gone the way of the Dodo bird?
Turcsanyi L et al. Leukemia, March 2026 (epub ahead of print)
open access publication
FBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Li X et al. Cell Rep, March 2026
open access publication
Transcriptional readthrough precedes alternative splicing programs triggered in chronic myeloid leukemia cells imatinib
Podszywalow-Bartnicka P et al. Sci Adv, March 2026
open access publication
Treatment of K562 cells with ABL kinase inhibitors reveals differential metabolic profiles
Renukuntla P et al. Drug Res (Stuttg.), March 2026
Targeting mitochondrial vulnerabilities in chronic myeloid leukemia: From pathobiology to novel therapeutic opportunities
Caprino F et al. Cancers(Basel), March 2026
open access publication
Activated memory cytotoxic T-lymphocyte and T-cell receptor Vβ clonality predict treatment-free remission after TKI discontinuation in chronic-phase chronic myeloid leukemia: A 1-year prospective immune-monitoring study
Jo T et al. Int J Mol Sci, March 2026
open access publication
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia
Park J et al. Leukemia, March 2026
open access publication
February
Intrinsic cellular resistance to BCR::ABL1 inhibitors
Cruz-Rodriguez N et al. Haematologica, February 2026 (epub ahead of print)
open access publication
ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib
Roy R et al. Exp Hematol, February 2026
High miR-202-5p expression at initial diagnosis is associated with tyrosine kinase inhibitor resistance in chronic myeloid leukemia – a result from a nested Case-Control Study
Nie ZY et al. EJHaem, February 2026
open access publication
Deep cytomorphology identifies erythroid skewing and monocytic morphology to predict TKI sensitivity in CML patients
Luukkainen K et al. Hemasphere, February 2026
open access publication
Peripheral blood neutrophil maturation as a predictor of treatment-free remission in CML
Fujita M et al. Int J Lab Hematol, February 2026 (epub ahead of print)
Potential utility of PPARγ agonists in targeting chronic myeloid leukemia stem cells
Atef B et al. Ann Hematol, February 2026
open access publication
Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity
Hossain MF et al. Exp Hematol Oncol, February 2026
open access publication
ATTEC-mediated degradation of BCR-ABL in chronic myeloid leukemia cells
Wang Z et al. Eur J Med Chem, February 2026
Integrative multi-omics analysis of long non-coding RNA regulatory networks in chronic myeloid leukemia resistance and leukemic stem cell persistence
Soltani I et al. Comput Biol Chem, February 2026
Asciminib and pulsed ATRA as post-remission therapy in T3151I mutated PML_RARA-positive blast crisis of chronic myeloid leukemia
Mazzarella R et al. Ann Hematol, February 2026
open access publication
Quantitative reverse transcription PCR compared with high-resolution melting for simultaneous detection and quantification of four isoforms of BCR::ABL1
Zhou T et al. J Clin Pathol, February 2026
Dual proteasome and histone deacetylase inhibition overcomes tyrosine kinase inhibitor resistance in breakpoint cluster region: Abdelson 1-driven leukaemia cell lines
Okabe S et al. J Cell Mol Med, February 2026
open access publication
January
Hsp-70 Bim interaction mediated mitophagy as a potential therapeutic target for CML stem cells
Song T et al. Stem Cell Reports, January 2026
open access publication
Enhanced detection of splice-altering variants in hematologic malignancies using targeted RNA-sequencing data
Maqsood M et al. J Mol Diagn, January 2026
Identification of a Mushashi2 translocation as a novel oncogene in myeloid leukemia
Spinler K et al. Elife, January 2026
open access publication
Quantitative reverse transcription PCR completed with high-resolution melting for simultaneous detection and quantification of four isoforms of BCR::ABL1
Zhou T et al. J Clin Pathol, January 2026 (epub ahead of print)
Sequential BCR::ABL1 evaluation during dose de-escalation in peripheral blood is more predictive of TFR success than single assessment at dose de-escalation in either peripheral blood or bone marrow
Patterson SD et al. Blood, January 2026 (epub ahead of print)
open access publication
Mmrn1 expression defines a novel subset of hematopoietic stem cells and leukemia stem cells with great self-renewal potential
Chen N et al. Haematologica, January 2026 (epub ahead of print)
open access publication
2026 Low- and Middle-Income Countries Publications
Worldwide Publications of Interest
Chronic myeloid leukemia in low- and middle-income countries
Mahon FX et al. N Engl J Med, June 2026
Chronic myeloid leukemia in resource-limited settings: Navigating treatment challenges amit limited tyrosine kinase inhibitor access
Aamir Z et al. J Int Med Res, June 2026 – open access publication
Benefits and perils of generic drugs for hematologic neoplasms and their use in low- and middle-income countries: a narrative review
Malhotra H. and Burli A., Blood Global Hematology, June 2026 – open access publication
Treatment-free remission in chronic myeloid leukemia in low- and middle-income countries
Annamalay A et al. N Engl J Med, March 2026
open access publication
Next-generation sequencing from chronic myeloid leukemia dried blood spots: Insights and implications for global oncology
Oehler VG et al. Leukemia, January 2026 (epub ahead of print)
CML Publications from Africa
BCR-ABL1 transcript variants in chronic myeloid leukemia patients in Africa: A systematic review
Emeline Oloume M et al. Health Sci Rep, July 2026
open access publication
Long-term survival and successful pregnancy in a Nigerian women with concurrent diagnosis of non-Hodgkin lymphoma and chronic myeloid leukemia:
a care report
Ahmed IO et al. J Med Case Rep, January 2026
open access publication
CML Publications from the Middle East
Real-world data on the use of asciminib in chronic-phase chronic myeloid leukemia after two or more prior tyrosine kinase inhibitors: Results of the Turkish managed access program along with a literature review
Özmen D et al. Leuk Res, July 2026
Genetic and non-genetic correlates of imatinib pharmacokinetics and side effects of imatinib in Palestinian patients with chronic myeloid leukemia
Adawi DH et al. Biochem Genet, April 2026
CML Publications from Asia
Study on efficacy and safety of dasatinib 50 mg in newly diagnosed patients with chronic myeloid leukemia (CML) in chronic phase (CP): Experience from a tertiary care hospital
Banarjee A et al. Indian J Hematol Blood Transfus, July 2026
Optimizing treatment-free remission (TFR) in chronic myeloid leukemia: Challenges and a modified monitoring strategy – real-world data from Eastern India
Parihar M et al. Indian J Haematol Blood Transfus, July 2026
Decoding BCR::ABL1 kinase domain mutations in chronic myeloid leukemia: Implications for tyrosine kinase inhibitor resistance in a South Asian population
Sharif F et al. Hematol Transfus Cell Ther, July 2026 (epub ahead of print)
open access publication
Clinical significance of the S348I mutation in BCR-ABL as a dominant variant in Indonesian CML patients under tyrosine kinase inhibitor therapy: A Cohort Study
Harjianti T et al. Asian Pac J Cancer Prev, February 2026
open access publication
Impact of bone marrow fibrosis on the outcomes of chronic myeloid leukemia treated with second generation tyrosine kinase inhibitors
Fayyaz F et al. Indian J Hematol Blood Transfus, January 2026
CML Publications from Latin America
Impact of the changes in chronic myeloid leukemia classification proposed by the 2022 World Health Organization: a single-center Brazilian study
Emiliano EG et al. Hematol Transfus Cell Ther, May 2026 (epub ahead of print)
– open access publication
Breaking barriers: Reducing cost and overcoming challenges in BCR::ABL1 monitoring for chronic myeloid leukemia in Brazil
Etges APBDS et al. JCO Glob Oncol, April 2026 - open access publication
Real-life data of patients with chronic myeloid leukemia in Amazonas
Abreu RS et al. BMC Cancer, March 2026 (epub ahead of print)
open access publication
2026 Pediatric CML Publications
July
Therapeutic drug monitoring of imatinib in paediatric chronic myeloid leukemia: Towards practical implementation and interpretation of measured plasma concentrations
Lensker P et al. Clin Pharmacokinet, July 2026 – open access publication
Treatment patterns and outcomes of pediatric chronic myeloid leukemia in a Brazilian multicentre cohort
da Silva MEM et al. Pediatr Blood Cancer, July 2026 (epub ahead of print)
June
Prepubertal initiation of imatinib is associated with reduced final height in children with chronic myeloid leukemia
Sadanand R et al. Pediatr Hematol Oncol, June 2026 (epub ahead of print)
May
Therapeutic drug monitoring of imatinib in pediatric chronic myeloid leukemia: Towards practical implementation and interpretation of measured plasma concentrations
Lensker P et al. Clin Pharmacokinet, May 2026 (epub ahead of print)
– open access publication
April
Prevalance and characterization of germline RAS pathway variants in children with chronic myeloid leukemia
Ghete T et al. Leukemia, April 2026 (epub ahead of print) – open access publication
March
Long-term outcomes of chronic myeloid leukemia in children and adolescents – real-world data from a single-institute in Taiwan
Yang YN et al. J Farmos Med Assoc, March 2026
open access publication
January
How I treat chronic myeloid leukemia in children and adolescents
(Chen J et al. Blood, January 2026)
Predictors of response to imatinib therapy and long-term outcomes in pediatric and adolescent patients with CML
(Saha S et al. Cancer Rep Hoboken, January 2026)
Safety profiles of dasatinib in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database
(Yang Y et al. Jpn J Clin Oncol, January 2026)
CML and COVID-19
Immune response to SARS-CoV-2 vaccination among chronic myeloid leukemia patients on tyrosine kinase inhibitors
Cheong CS et al. Ann Acad Med Singap, April 2026 (epub ahead of print) – open access publication