Pediatric Case Reviews

The iCMLf Paediatric Case Review Series presents cases of children with CML treated in low- and middle-income countries, discussed by experts from the International CML Foundation. The series is designed to provide a comprehensive exploration of challenging paediatric CML cases from multiple perspectives, with the aim of strengthening knowledge and supporting improved patient outcomes.

Case #2 - Treatment free remission after 9 years without deep molecular response

Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 2: Treatment-Free Remission After 9 Years of Imatinib Treatment Without Prior Achievement of Sustained Deep Molecular Response
Michalowski MB et al. Case Reports in Oncological Medicine, March 2025
open access publication

The second review highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response. 

Case #1 - Boy presenting with priapism and loss of vision

Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 1: A Boy Presenting With Priapism and Loss of Vision
Roy Moulik et al. Case Reports in Oncological Medicine, July 2024
open access publication

This landmark case discusses a 14-year-old boy from India diagnosed with CML complicated by priapism and loss of vision.