CML Publications of the Month
As part of our monthly news service we would like to make you aware of important CML publications. From the many papers published every month Professor Tim Hughes selects topical, interesting papers for your perusal. Papers with a clinical, scientific, pediatric and low and middle income country focus are shared.
March 2026
Clinical CML papers
Asciminib demonstrates superior efficacy and safety in newly diagnosed chronic myeloid leukemia in the ASC4FIRST trial
Cortes JE et al. Blood, March 2026
open access publication
Imatinib outcomes in chronic myeloid leukemia across diverse healthcare settings: A systematic review and meta-analysis
Miranda-Galvis M et al. Blood Cancer J, March 2026
open access publication
Introducing a prognostic score for successful treatment-free remission in chronic myeloid leukemia
Claudiani S et al. Br J Haematol, March 2026 (epub ahead of print)
open access publication
Shared identity and patient care: adherence to guideline-recommended biomarker testing in chronic myeloid leukemia
Montano-Campos JF et al. J Natl Canc Netw, March 2026
open access publication
Predictive biomarkers of sustained treatment-free remission in chronic myeloid leukemia: gene expression analyses from the ENESTfreedom and ENESTop studies
Radich JP et al. Haematologica, March 2026 (epub ahead of print)
open access publication
Imatinib and nilotinib are equally successful in achieving treatment-free remission
Cheng F et al. Blood Cancer J, March 2026
open access publication
Tyrosine kinase inhibitors, chronic myeloid leukemia, and pregnancy: pharmacotherapeutic challenges and recommendations
Haddad FG et al. Expert Opin Pharmacother, March 2026 (epub ahead of print)
Management of chronic myeloid leukemia with tyrosine kinase inhibitors: adverse events, toxicities and therapy dosing
Oehler VG et al. Haematologica, March 2026 (epub ahead of print)
open access publication
Restless leg syndrome in chronic myeloid leukemia: an overlooked condition with a significant impact on health-related quality of life
Gürer T et al. Ann Hematol, March 2026
open access publication
Very long-term outcomes of chronic-phase chronic myeloid leukemia patients treated with imatinib: A 25-year real-world cohort study
Costa A et al. Br J Haematol, March 2026 (epub ahead of print)
Outcomes of patients treated with dasatinib 50 mg/d: A Pooled Analysis
Haddad FG et al. Clin Lymphoma Myeloma Leuk, March 2026 (epub ahead of print)
Five-year analysis of J-SKI: an observational study of TKI discontinuation in patients with CML in Japan
Takahashi N et al. Int J Hematol, March 2026 (epub ahead of print)
open access publication
Beyond ATP: asciminib and the allosteric path in CML
Abruzzese E et al. Blood, March 2026
ELN 2025 and somatic NGS in CML: a pragmatic framework for selective testing and interpretation beyond BCR::ABL1
Mishra S et al. Leuk Lymphoma, March 2026 (epub ahead of print)
Scientific CML papers
Chronic myeloid leukemia: have basophils gone the way of the Dodo bird?
Turcsanyi L et al. Leukemia, March 2026 (epub ahead of print)
open access publication
FBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Li X et al. Cell Rep, March 2026
open access publication
Transcriptional readthrough precedes alternative splicing programs triggered in chronic myeloid leukemia cells imatinib
Podszywalow-Bartnicka P et al. Sci Adv, March 2026
open access publication
Treatment of K562 cells with ABL kinase inhibitors reveals differential metabolic profiles
Renukuntla P et al. Drug Res (Stuttg.), March 2026
Targeting mitochondrial vulnerabilities in chronic myeloid leukemia: From pathobiology to novel therapeutic opportunities
Caprino F et al. Cancers(Basel), March 2026
open access publication
Activated memory cytotoxic T-lymphocyte and T-cell receptor Vβ clonality predict treatment-free remission after TKI discontinuation in chronic-phase chronic myeloid leukemia: A 1-year prospective immune-monitoring study
Jo T et al. Int J Mol Sci, March 2026
open access publication
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia
Park J et al. Leukemia, March 2026
open access publication
Pediatric CML papers
Long-term outcomes of chronic myeloid leukemia in children and adolescents – real-world data from a single-institute in Taiwan
Yang YN et al. J Farmos Med Assoc, March 2026
open access publication
LMIC CML papers
Treatment-free remission in chronic myeloid leukemia in low- and middle-income countries
Annamalay A et al. N Engl J Med, March 2026
open access publication
Real-life data of patients with chronic myeloid leukemia in Amazonas
Abreu RS et al. BMC Cancer, March 2026 (epub ahead of print)
open access publication