CML Publications of the Month

As part of our monthly news service we would like to make you aware of important CML publications. From the many papers published in July, Professor Jerry Radich has selected topical, interesting papers for your perusal. Papers with a clinical, scientific, pediatric and low and middle income country focus are shared.

Professor Jerald Radich

July 2026

Clinical CML papers

Introduction to the review series. Chronic myeloid leukemia in 2026
Radich J. Haematologica, July 2026 
open access publication

Favorable tolerability of Asciminib versus ATP-competitive tyrosine kinase inhibitors in the ASC4FIRST study of newly diagnosed patients with chronic-phase chronic myeloid leukemia
Issa GC et al. Haematologica, July 2026 (epub ahead of print) 
open access publication

Asciminib monotherapy in patients with BCR::ABL1 T315I-mutated chronic-phase chronic myeloid leukemia: phase 1 trial final results
Cortes JE et al. Leukemia, July 2026 (epub ahead of print) 
open access publication

Five-year follow-up of OPTIC: long-term efficacy, safety, and mutation analyses of ponatinib in chronic-phase chronic myeloid leukemia from a randomized phase 2 trial
Kantarjian H et al. Leukemia, July 2026 (epub ahead of print) 
open access publication

Diabetic patients with newly diagnosed chronic myeloid leukemia: TKI choice and early adverse events. A real-life survey with the Italian CML Network
Russo S et al. Eur J Haematol, July 2026 (epub ahead of print) 

Development and external validation of a transcriptome-based multivariable prediction model for treatment-free remission in chronic myeloid leukemia
Alcazer V et al. J Clin Oncol, July 2026

Reattempt of tyrosine kinase inhibitor discontinuation after maintenance therapy with ponatinib in patients with chronic myeloid leukemia in the chronic-phase: Results of the Japan Adult Leukemia Study Group RE-STOP219 Study
Iriyama N et al. Br J Haematol, July 2026 (epub ahead of print) 
open access publication

Olverembatinib: real progress in BCR::ABL1 leukemia?
Oehler VG et al. Haematologica, July 2026 (epub ahead of print) 
open access publication

Frontline nilotinib versus dasatinib in newly diagnosed chronic phase chronic myeloid leukemia: A propensity score analysis based on Agenzia Italiana del Formaco Monitoring Registries
Breccia M et al. Clin Lymphoma Myeloma Leuk, July 2026 

Ponatinib safety profile: An analysis of 10 years of real-world experience
Jabbour E et al. Drug Saf, July 2026 (epub ahead of print) 
open access publication

Dynamic improvement of the treatment-free remission prognostic score by prolonging MR4 duration in chronic myeloid leukemia
Fujita M and Ureshino H. Br J Haematol, July 2026

Real-world evidence-based study on treatment-free remission in chronic myeloid leukemia
Cheng F et al. J Natl. Compr Canc Netw, July 2026 (epub ahead of print) 
open access publication

Scientific CML papers 

Improved inter-lab precision after CML international scale adaptation: a 15-year history of BCR::ABL1 proficiency testing
Kim AS et al. Leukemia, July 2026 (epub ahead of print) 
open access publication

Development and validation of an in-house one-step RT-qPCR method for the quantification of the BCR::ABL1 p210 transcripts
Damerchiloo F et al. Sci Rep, July 2026 (epub ahead of print) 
open access publication

Measurable residual disease and the unresolved biology of leukemic stem cells
Bhartiya D et al. Stem Cell Rev Rep, July 2026 (epub ahead of print)

Genetic Profile, Treatment Response, and Outcomes of BCR::ABL1-Positive Mixed-Phenotype Acute Leukemia: A Study From the BCR::ABL1 Pathology Group 
Shen Q., et al. Modern Pathology, May 2026
open access publication

Pediatric CML papers

Therapeutic drug monitoring of imatinib in paediatric chronic myeloid leukemia: Towards practical implementation and interpretation of measured plasma concentrations
Lensker P et al. Clin Pharmacokinet, July 2026 – open access publication

Treatment patterns and outcomes of pediatric chronic myeloid leukemia in a Brazilian multicentre cohort
da Silva MEM et al. Pediatr Blood Cancer, July 2026 (epub ahead of print)

LMIC CML papers 

Real-world data on the use of asciminib in chronic-phase chronic myeloid leukemia after two or more prior tyrosine kinase inhibitors: Results of the Turkish managed access program along with a literature review
Özmen D et al. Leuk Res, July 2026

BCR-ABL1 transcript variants in chronic myeloid leukemia patients in Africa: A systematic review
Emeline Oloume M et al. Health Sci Rep, July 2026 
open access publication

Study on efficacy and safety of dasatinib 50 mg in newly diagnosed patients with chronic myeloid leukemia (CML) in chronic phase (CP): Experience from a tertiary care hospital
Banarjee A et al. Indian J Hematol Blood Transfus, July 2026 

Optimizing treatment-free remission (TFR) in chronic myeloid leukemia: Challenges and a modified monitoring strategy – real-world data from Eastern India
Parihar M et al. Indian J Haematol Blood Transfus, July 2026

Decoding BCR::ABL1 kinase domain mutations in chronic myeloid leukemia: Implications for tyrosine kinase inhibitor resistance in a South Asian population
Sharif F et al. Hematol Transfus Cell Ther, July 2026 (epub ahead of print) 
open access publication
 

Previous papers

June 2026

May 2026

April 2026

March 2026

February 2026

January 2026

December 2025

November 2025

September-October 2025

August 2025

July 2025

June 2025

May 2025

April 2025

March 2025

February 2025

January 2025