As part of our monthly news service we would like to make you aware of the CML publications of the month. From the many papers published every month Professor Timothy Hughes has selected topical, interesting papers for your perusal.

Read Professor Hughes' CML publications of the month: February 2026

Clinical CML papers

• Development of a prognostic scoring system for chronic myeloid leukemia in blast phase
  Lauseker M et al. Leukemia, February 2026 (epub ahead of print) – open access publication
• A plain language summary of how the body processes a lower-dose nilotinib tablet (DanzitenTM) compared with the existing capsule (Tasigna®)
  Mauro M et al. Future Oncol, February 2026
• Second attempt to discontinue TKI after molecular relapse in patients with chronic myeloid leukemia: A real-life Italian multicenter study
  Iurlo A et al. Cancer, February 2026 – open access publication
• Extended long-term follow-up and the survival of Stop Imatinib Study
  Mahon FX et al. Blood Neoplasia, February 2026 – open access publication
• Leveraging model-informed drug development to predict asciminib efficacy in second-line treatment of chronic myeloid leukemia in chronic phase
  Sy SKB et al. Clin Pharmacokinet, February 2026 (epub ahead of print)
• Pregnancy-related adverse events with tyrosine kinase inhibitor use in chronic myeloid leukemia: A FAERS Pharmacovigilance analysis (2001 – 2024)
  Faisal MS et al. Clin Lymphoma Myeloma Leuk, February 2026
• Efficacy and safety of 50 mg versus 100 mg daily frontline dasatinib therapy in chronic-phase chronic myeloid leukemia: a non-controlled, observational dose-comparable cohort study
  Cheng F et al. BMC Cancer, February 2026 (epub ahead of print) – open access publication
• Second- and third-generation BCR-ABL tyrosine kinase inhibitors and the risk of pulmonary arterial hypertension: A prevalent new-user design
  Jambon-Barbara C et al. Circulation, February 2026 (epub ahead of print) – open access publication
• A BCR::ABL1 exon 13 variant leads to systematic underestimation of transcript level in the molecular monitoring of CML
  Boucher L et al. Leuk Res, February 2026 (epub ahead of print)
• Evolving therapeutic algorithms in chronic myeloid leukemia: Integrating efficacy, safety, and survivorship
  Leyfman Y et al. Biomedicines, February 2025 – open access publication
• The importance of bone marrow biopsy for chronic myeloid leukemia classification – a case report
  Gonçalves NY et al. HJ Hematop, February 2026 – open access publication
• Should you be afraid of the big bad wolf? A practical real-world review for the comfortable use of bosutinib in the therapy of chronic myeloid leukemia
  Lipton JH. J Cancer Immunol, December 2025 – open access publication
  

Scientific CML papers

• Intrinsic cellular resistance to BCR::ABL1 inhibitors
  Cruz-Rodriguez N et al. Haematologica, February 2026 (epub ahead of print) – open access publication
• ERK-mTOR crosstalk suppresses autophagy and upregulates proteasomal degradation pathway to confer chronic myeloid leukemia cells resistant to imatinib
  Roy R et al. Exp Hematol, February 2026
• High miR-202-5p expression at initial diagnosis is associated with tyrosine kinase inhibitor resistance in chronic myeloid leukemia – a result from a nested Case-Control Study
  Nie ZY et al. EJHaem, February 2026 – open access publication
• Deep cytomorphology identifies erythroid skewing and monocytic morphology to predict TKI sensitivity in CML patients
  Luukkainen K et al. Hemasphere, February 2026 – open access publication
• Peripheral blood neutrophil maturation as a predictor of treatment-free remission in CML
  Fujita M et al. Int J Lab Hematol, February 2026 (epub ahead of print)
• Potential utility of PPARγ agonists in targeting chronic myeloid leukemia stem cells
  Atef B et al. Ann Hematol, February 2026 – open access publication
• Molecular background of Philadelphia chromosome dependent enhancement of cellular growth and tyrosine kinase inhibitor sensitivity
  Hossain MF et al. Exp Hematol Oncol, February 2026 - open access publication