Session Summaries from the ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and TherapyWe're bringing you highlights from the recent ESH-iCMLf 27th Annuzal John Goldman Conference on CML: Biology and Therapy with a summary of selected scientific sessions.
Chair: Mary Scott (Glasgow)
This session explored new insights into leukemic stem cell biology, persistence, and the bone marrow microenvironment in CML. The speakers presented novel models and molecular mechanisms driving stem cell survival and relapse, highlighting inflammatory, metabolic, and stromal interactions shaping disease behaviour and treatment-free remission (TFR) potential.
2025 John Goldman Fun Run - Thank you to everyone who joined the 2025 John Goldman Run Run, held during the recent ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy in Estoril.
This year’s Run was a huge success!
More than 50 participants set off before sunrise for a 5-km run along the scenic seaside route, proudly wearing this year’s purple Fun Run charity t-shirts.
Together, we raised $2,900 – more funds than ever before – in support of the iCMLf programs that improve access to CML education and care in low- and middle-income countries.
A heartfelt thank you to all our individual supporters.

As the ESH-iCMLf 27th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy approaches, we are excited to share what’s in store for this year in Estoril, Portugal. We look forward to seeing you there!
From October 10–12, the meeting will once again bring together leading experts to present the latest discoveries in CML biology, innovative treatment strategies, and insights from clinical trials and real-world practice. Expect a vibrant exchange of knowledge, engaging scientific debates, and plenty of opportunities to connect with colleagues from around the world.
And for those who can’t be in Estoril, or want to revisit the day’s key sessions,
the iCMLf will provide daily highlights and session summaries.
Follow us on social media and on the iCMLf website.
27th Annual John Goldman Conference on CML: Biology and Therapy – A first look at the programThis October, the CML community will come together in Estoril, Portugal for the ESH-iCMLf 27th Annual John Goldman Conference on Chronic Myeloid Leukemia: Biology and Therapy (October 10-12, 2025).
While the program is still being refined by the conference Chairs and Co-organizers, we wanted to give you a flavour of the exciting sessions you can look forward to.
As always, the meeting will be a hub for sharing the latest scientific advancements on CML and fostering collaboration across the global CML network. Building on the strong tradition of scientific excellence, the 2025 program will feature cutting-edge research, interactive workshops, and prize lectures from leaders shaping the future of CML biology and therapy.
We are delighted to share a first glimpse of the program and speakers with you.
Start your confernce experience at the ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy on the right foot - literally!
Lace up for the John Goldman Fun Run on Sunday morning, October 12, before the sessions begin. Organised by the iCMLf, the 5-km run is a fun and meaningful way to connect with colleages while supporting young CML researchers and physicians from low- and middle-income countries.
Secure your place now and be part of a great team of runners!