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CML Guidelines

CML practitioners need dependable, well researched information to help make the best decisions for their CML patients. International therapeutic guidelines on the management of CML based on the latest research and written by leading CML experts provide a reliable and independent source of information. 

This section provides access to a selection of relevant international CML guidelines designed to assist you in the management of your CML patients. These guidelines include: 

  • European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia
  • NCCN Clinical Practice Guidelines in Oncology: CML version 1.2024
  • Chronic myeloid leukemia ESMO clinical practice guidelines for diagnosis, treatment and follow-up 2017
  • Guidelines and recommendations for pediatric CML
  • NICE - National Institute for Health and Care Excellence Guidances

If you have additional information to provide, please contact us at info@cml-foundation.org

European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

Hochhaus A et al. Leukemia 2020;34(4):966-984

Click here to see the 2020 recommendations

Chronic Myeloid Leukemia NCCN Clinical Practice Guidelines

Click here to view the NCCN Guidelines
(Version 1.2024 - August 1, 2023)

Click here to view the NCCN Guidelines for Patients
(Version 2023)

ESMO Guidelines

Chronic Myeloid Leukemia: ESMO clinical practice guidelines for diagnosis, treatment and follow-up

Hochhaus A et al. Ann Oncol 2017 1;28(suppl_4): iv41-iv51


Click here to view the full publication


NICE - National Institute for Health and Care Excellence

NICE Guidance: Asciminib for treating myeloid leukemia after 2 or more tyrosine kinase inhibitors
Published August 2022

Click here to view the full guidance

Click 'Read more'  to find more NICE guidances

Pediatric Guidelines

International pediatric panel recommendations
Management of children and adolescents with chronic myeloid leukemia in blast phase
Sembill S et al. Leukemia, 2023;37:505–517
Click here to view the full publication

Children's Oncology Group CML Working Group
Management of CML in childen and adolescents
Athale U et al. Pediatr Blood Cancer 2019 Sep;66(9):e27827
Click here to view the full publication