As part of our monthly news service we would like to make you aware of the CML publications of the month. From the many papers published every month Professor Timothy Hughes has selected topical, interesting papers for your perusal that also include interesting papers from the LMICs.

Read Professor Hughes' CML publications of the month: April 2025

Clinical CML papers

• Asciminib monotherapy in patients with chronic myeloid leukemia chronic-phase without BCR::ABL1 T315I treated with at least 2 prior tyrosine kinase inhibitors: Phase 1 final results
  Hochhaus A et al. Leukemia, April 2025 (epub ahead of print) – open access publication
• Asciminib in combination with imatinib, nilotinib, or dasatinib in patients with chronic myeloid leukemia in chronic or accelerated phase: Phase 1 study final results
  Cortes JE et al. Leukemia, April 2025 (epub ahead of print) – open access publication
• Olverembatinib in chronic myeloid leukemia – Review of historical development, current status, and future research
  Kantarjian H et al. Cancer, April 2025
• Successful treatment-free remission after ponatinib discontinuation in pretreated patients with chronic myeloid leukemia in chronic-phase
  Haddad FG et al. Clin Lymphoma Myeloma Leuk, April 2025
• CAR-T cell therapy in chronic myeloid leukemia patients with lymphoid blast crisis: A multicenter clinical analysis
  Liu Y et al. Cancer Lett, April 2025 (epub ahead of print)
• Prognostic scoring system in chronic myeloid leukemia – Review
  Lauseker M et al. Leukemia, April 2025 (epub ahead of print) – open access publication
• How I individualize treatment for chronic-phase CML
  Leyte-Vidal AM and Shah NP. Blood, April 2025 (epub ahead of print)
• Synergistic effect of asciminib with reduced doses of ponatinib in human Ph+ myeloid leukemia with the T315M mutation
  Nguyen T et al. Int J Hematol, April 2025 (epub ahead of print) – open access publication
• Tyrosine kinase inhibitor treatment patterns in patients with chronic-phase chronic myeloid leukemia:
  A single centre data from China
  Yuan MY et al. Clin Lymphoma Myeloma Leuk, April 2025

Scientific CML papers 

• SMAC mimetics in action in chronic myeloid leukemia
  Turhan AG. Blood, April 2025
• SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability
  Mancini M et al. Clin Transl Med, April 2025 – open access publication
• Timing and trajectory of BCR::ABL1-driven chronic myeloid leukemia
  Kamizela AE et al. Nature, April 2025 – open access publication

LMIC CML papers

• Allogeneic transplantation for CML blast phase learnings over last decade from a single centre in North India
  Patra PC et al. Ann Hematol, April 2025 (epub ahead of print) – open access publication
• Effect of imatinib mesylate on the ovarian reserves of female patients with chronic myeloid leukemia
  Satija T et al. Indian J Hematol Blood Transf, April 2025
• The Influence of the COVID-19 Pandemic in NK Cell Subpopulations from CML Patients Enrolled in the Argentina Stop Trial
  Belén Sanchez M et al. Cells, April 2025 – open access publication