CML Publications from Africa

• Chronic myeloid leukemia kinase mutations: A retrospective descriptive study on the therapeutic and prognostic significance in patients of King VIII Hospital, KwaZulu-Natal, South Africa
  Benjamin C et al. Health Sci Rep, June 2023 – open access publication
• A study to explore the role of IDH1 (R132) mutation on imatinib toxicity and effect of ABCG2/OCT1 expression on N-Desmethyl imatinib plasma level in Egyptian chronic myeloid leukemia patients
  Sabri A et al. Drug Res (Stuttg.), March 2023
• Assessment of molecular response to tyrosine kinase inhibitors in Tunisian patients with chronic myeloid leukemia
  Frikha R et al. J Oncol Pharm Pract, December 2022
• A ten-year experience of treating chronic myeloid leukemia in rural Rwanda: Outcomes and insights for a changing landscape
  Morgan J et al. JCO Glob Oncol, July 2022
• Baseline blood count levels increase odds of cytopenia among CML patients in Kenya: a case control study
  McLigeyo A et al. BMC Cancer, February 2022 – open access publication

• Spectrum of BCR-ABL mutations and treatment outcomes in Ethiopian Imatinib-resistant patients with chronic myeloid leukemia
  Tadesse F et al. JCO Glob Oncol, July 2021 - open access publication
• Managing pediatric chronic myeloid leukemia in Africa: the Botswana experience with two cases
  Kaang T et al. Pediatr Hematol Oncol, March 2021 (epub ahead of print)
• Molecular response to imatinib in patients with chronic myeloid leukemia in Tanzania
  Nasser A et al. Blood Adv, March 2021 – open access publication
• Imatinib in the treatment of chronic myeloid leukemia in Morocco
  Dakkoune M et al. Bull Cancer, September 2020 (in French)
• Early molecular response in East African Philadelphia chromosome-positive chronic myeloid leukemia patients treated with imatinib and barriers to access treatment
  Henke O et al. ecancer, August 2020 – open access publication
• Micro RNA 30a mediated autophagy and imatinib response in Egyptian chronic myeloid leukemia patients
  Khalil NA et al. Indian J Hematol Blood Transfus, July 2020
• Two decades of experience in a combined adult/pediatric allogeneic hematopoietic stem cell transplantation center in Algiers, Algeria
  Benakli M et al. Ann Hematol, March 2020
• The prognostic significance of TET2 single nucleotide polymorphism in Egyptian chronic myeloid leukemia
  Hamed NA et al. Mediterr J Hematol Infect Dis, January 2020 – open access publication
• Pre-therapeutic and evolutive characteristics of patients suffering from chronic myeloid leukemia in Abidjan, Ivory Coast
  Silué DA et al. Bull Cancer, June 2019 (in French)
• Acute ischemic intestinal necrosis as a rare side effect of nilotinib
  Li L et al. Niger J Clin Pract, January 2019
• Detection of BCR-ABL1 fusion gene transcripts in the saliva of Nigerian patients with chronic myeloid leukemia
  Uzoma IC et al. Niger J Clin Pract, January 2019
• Inter-individual variation in imatinib disposition: any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients?
  Adehin A et al. Leuk Lymphoma, May 2018
  (epub ahead of print)
• Chronic myeloid leukemia patients in Tunisia: epidemiology and outcome in the imatinib era (a multicentric experience)
  Ben Lakhal R et al. Ann Hematol, January 2018
  (epub ahead of print)
• Population pharmacokinetics of imatinib in Nigerians with chronic myeloid leukemia: Clinical implications for dosing and resistance
  Adeagbo BA et al. J Clin Pharmacol, December 2017
• Preliminary data on mircoRNA profiles in a group of South African patients diagnosed with chronic myeloid leukemia
  Prinsloo A et al. Mol Clin Oncol, September 2017 
• Downregulation of miR-451 in Tunesian chronic myeloid leukemia patients: potential implications in imatinib resistance
  Soltani I et al. Hematology, May 2018 
• hOCT1 gene expression predict for optimal response to imatinib in Tunisian patients with chronic myeloid leukemia
  Ben Hassine I et al. Cancer Chemother Pharmacol, April 2017 
• Epidemiological approach of chronic myeloid leukemia: Algerian-Tunesian Study
  Djouadi K et al. Blood, December 2016 
• Evaluation of the imatinib treatment of patients followed up for chronic myelogenous leukemia in Algeria
  Djouadi K et al. Blood, December 2016 
• Influence of CYP3A*3 and ABCB1 C3435T on clinical outcomes and through plasma concentrations of imatinib in Nigerians with chronic myeloid leukemia
  Adeagbo BA et al. J Clin Pharm Ther, October 2016
• Simple HPLC-UV method for pharmacokinetic studies of imatinib in the presence of common antimalarial agents
  Adeagbo BA et al. Journal of Liquid Chromatography & Related Technologies 2015, 38:1194-1198

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