Out of a total of about 300 plus patients of CML on treatment at our center, 2 are HIV positive and are on HART.
Both are on Imatinib 400 mg/day and tolerating the well.
No experience with the 2nd Gen TKIs.
The problem for the patient is taking too many drugs per day leading to compliance issues.
Also, anemia, because of the ART or Imatinib, is an issue in these patients.
No other issues with toxicities or responses.