Please see below for a selection of interesting articles on pediatric CML in peer-reviewed journals.

We are delighted to share the second case review in our series dedicated to the treatment of pediatric CML (pCML) in low and middle-income countries (LMICs) that highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response.

Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 2: Treatment-Free Remission After 9 Years of Imatinib Treatment Without Prior Achievement of Sustained Deep Molecular Response.
Michalowski, MB et al. Case Reports in Oncological Medicine, March 2025 – open access publication

This series of pediatric CML case reviews aims to provide a comprehensive discussion of challenging pCML cases from various perspectives to enhance knowledge and improve patient outcomes.

Other latest publications include:

• Complications at diagnosis of pediatric chronic myeloid leukemia in chronic phase
  Roy Moulik N et al. Pediatr Blood Cancer, August 2025 (epub ahead of print) – open access publication
• NAMP-mediated deacetylation of HSLS1 protein promotes clonogenic growth of pediatric CML cells
  Samareh B et al. Exp Hematol, August 2025 – open access publication
• Somatic mutations and outcomes in chronic myeloid leukemia adolescent and young adults compared to children, adults, and BCR::ABL1-positive acute lymphoblastic leukemia
  Krizkova J et al. Leukemia, July 2025 – open access publication
• Long-term endocrine outcomes and quality of life in pediatric and young chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy: A prospective study from India
  Mohan R et al. Front Oncol, July 2025 – open access publication
• Rare manifestations of pediatric chronic myeloid leukemia: A case report on priapism and a literature review
  Budair R et al. Front Oncol, June 2025 – open access publication
• Quality of life and adherence to tyrosine kinase inhibitors among pediatric, adolescent, and young adult chronic myeloid leukemia patients: 
  A systematic Review
  Werk RS et al. Pediatr Blood Cancer, June 2025 – open access publication
• Survival of European children, adolescents, and young adults diagnosed with haematological malignancies in the period 2000 – 2013: Results from EUROCARE-6, a population based study
  Trama A et al. Eur J Cancer, June 2025 – open access publication
• Genomic variant profiling in blast-phase paediatric chronic myeloid leukemia: Predisposing and driving alterations
  Behrens YL et al. Br J Haematol, May 2025 (epub ahead of print) – open access publication
• Allogeneic hematopoietic stem cell transplantation in pediatric and young adult patients with chronic myeloid leukemia in tyrosine kinase inhibitor er: A study of the Korean Blood and Marrow Transplantation Registry
  Ju HY et al. Cancer Res Treat, May 2025 (epub ahead of print) – open access publication
• Management of children and adolescents with chronic myeloid leukemia in chronic-phase: International pediatric chronic myeloid leukemia expert panel recommendations
  Millot F et al. Leukemia, March 2025 (epub ahead of print)
• Therapeutic drug monitoring of imatinib in pediatric chronic myeloid leukemia: Data from a real-world setting
  Suttorp M et al. Br J Haematol, March 2025 (epub ahead of print) – open access publication
• Favorable outcomes of de novo advanced phases of pediatric chronic myeloid leukemia in the tyrosine kinase inhibitor era
  Yoshikawa T et al. Int J Hematol, March 2025 (epub ahead of print) – open access publication
• Distribution of BCR::ABL1 transcript types and response to therapy in pediatric patients with chronic myeloid leukemia
  Seiser E et al. J Mol Diagn, January 2025 (epub ahead of print)
• Optimizing diagnostic tools and outcomes evaluation for t(9;22)-positive leukemias in pediatric low middle-income country (LMIC) patients
  Bukhari SI et al. Cancer Invest, January 2025 (epub ahead of print)
• Growth retardation and adult height in pediatric patients with chronic-phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
  Shima H et al. Leukemia, December 2024 (epub ahead of print)
• Treatment-free remissions in children with chronic myeloid leukemia (CML): 
  A prospective study from the Tata Memorial Hospital (TMA) Pediatric CML (pCML) cohort
  Roy Moulik N et al. Am J Hematol, November 2024 (epub ahead of print) – open access publication
• Clinical characteristics and outcomes of CML in adolescents and young adults
  Al Rabi K et al. Clin Lymphoma Myeloma Leuk, Oct 2024

Search here for more publications on pediatric CML