Please see below for a selection of interesting articles on pediatric CML in peer-reviewed journals.

We are delighted to share the second case review in our series dedicated to the treatment of pediatric CML (pCML) in low and middle-income countries (LMICs) that highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response.

Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 2: Treatment-Free Remission After 9 Years of Imatinib Treatment Without Prior Achievement of Sustained Deep Molecular Response.
Michalowski, MB et al. Case Reports in Oncological Medicine, March 2025 – open access publication

This series of pediatric CML case reviews aims to provide a comprehensive discussion of challenging pCML cases from various perspectives to enhance knowledge and improve patient outcomes.

Other latest publications include:

• Genomic variant profiling in blast-phase paediatric chronic myeloid leukemia: Predisposing and driving alterations
  Behrens YL et al. Br J Haematol, May 2025 (epub ahead of print) – open access publication
• Allogeneic hematopoietic stem cell transplantation in pediatric and young adult patients with chronic myeloid leukemia in tyrosine kinase inhibitor er: A study of the Korean Blood and Marrow Transplantation Registry
  Ju HY et al. Cancer Res Treat, May 2025 (epub ahead of print) – open access publication
• Management of children and adolescents with chronic myeloid leukemia in chronic-phase: International pediatric chronic myeloid leukemia expert panel recommendations
  Millot F et al. Leukemia, March 2025 (epub ahead of print)
• Therapeutic drug monitoring of imatinib in pediatric chronic myeloid leukemia: Data from a real-world setting
  Suttorp M et al. Br J Haematol, March 2025 (epub ahead of print) – open access publication
• Favorable outcomes of de novo advanced phases of pediatric chronic myeloid leukemia in the tyrosine kinase inhibitor era
  Yoshikawa T et al. Int J Hematol, March 2025 (epub ahead of print) – open access publication
• Distribution of BCR::ABL1 transcript types and response to therapy in pediatric patients with chronic myeloid leukemia
  Seiser E et al. J Mol Diagn, January 2025 (epub ahead of print)
• Optimizing diagnostic tools and outcomes evaluation for t(9;22)-positive leukemias in pediatric low middle-income country (LMIC) patients
  Bukhari SI et al. Cancer Invest, January 2025 (epub ahead of print)
• Growth retardation and adult height in pediatric patients with chronic-phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
  Shima H et al. Leukemia, December 2024 (epub ahead of print)
• Treatment-free remissions in children with chronic myeloid leukemia (CML): 
  A prospective study from the Tata Memorial Hospital (TMA) Pediatric CML (pCML) cohort
  Roy Moulik N et al. Am J Hematol, November 2024 (epub ahead of print) – open access publication
• Clinical characteristics and outcomes of CML in adolescents and young adults
  Al Rabi K et al. Clin Lymphoma Myeloma Leuk, Oct 2024
• A high proportion of germline variants in pediatric chronic myeloid leukemia in pediatric chronic myeloid leukemia
  Krumbhold M et al. Mol Cancer, Sept 2024 – open access publication
• CAR-T cells for the treatment of pediatric chronic myeloid leukemia in repeatedly relapsed lymphoid blast crisis
  Kramp LJ et al. Ann Hematol, Sept 2024 (epub ahead of print) – open access publication
• Low-level BCR::ABL1 transcript at diagnosis in childhood leukemia: A 10-year single institution study
  Cain LE et al. Genes Chromosomes Cancer, Sept 2024
• Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf) – Case No. 1: A Boy Presenting With Priapism and Loss of Vision
  Roy Moulik et al. Case Rep Oncol Med, July 2024 – open access publication
• Chronic myeloid leukemia in adolescents and young adults: Clinicopathological variables and outcomes
  Abdulla MA et al. Oncology, July 2024 (epub ahead of print) – open access publication
• Impact of tyrosine kinase inhibitors (TKIs) on growth in children and adolescents with chronic myeloid leukemia: A systematic review
  Katsarou D et al. Curr Pharm Des, July 2024 (epub ahead of print)

Search here for more publications on pediatric CML