Please see below for a selection of interesting articles on pediatric CML in peer-reviewed journals.
We are delighted to share the second case review in our series dedicated to the treatment of pediatric CML (pCML) in low and middle-income countries (LMICs) that highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response.
Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 2: Treatment-Free Remission After 9 Years of Imatinib Treatment Without Prior Achievement of Sustained Deep Molecular Response.
Michalowski, MB et al. Case Reports in Oncological Medicine, March 2025 – open access publication
This series of pediatric CML case reviews aims to provide a comprehensive discussion of challenging pCML cases from various perspectives to enhance knowledge and improve patient outcomes.
Other latest publications include:
- Management of children and adolescents with chronic myeloid leukemia in chronic-phase: International pediatric chronic myeloid leukemia expert panel recommendations
Millot F et al. Leukemia, March 2025 (epub ahead of print) - Therapeutic drug monitoring of imatinib in pediatric chronic myeloid leukemia: Data from a real-world setting
Suttorp M et al. Br J Haematol, March 2025 (epub ahead of print) – open access publication - Favorable outcomes of de novo advanced phases of pediatric chronic myeloid leukemia in the tyrosine kinase inhibitor era
Yoshikawa T et al. Int J Hematol, March 2025 (epub ahead of print) – open access publication - Distribution of BCR::ABL1 transcript types and response to therapy in pediatric patients with chronic myeloid leukemia
Seiser E et al. J Mol Diagn, January 2025 (epub ahead of print) - Optimizing diagnostic tools and outcomes evaluation for t(9;22)-positive leukemias in pediatric low middle-income country (LMIC) patients
Bukhari SI et al. Cancer Invest, January 2025 (epub ahead of print) - Growth retardation and adult height in pediatric patients with chronic-phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
Shima H et al. Leukemia, December 2024 (epub ahead of print) - Treatment-free remissions in children with chronic myeloid leukemia (CML):
A prospective study from the Tata Memorial Hospital (TMA) Pediatric CML (pCML) cohort
Roy Moulik N et al. Am J Hematol, November 2024 (epub ahead of print) – open access publication - Clinical characteristics and outcomes of CML in adolescents and young adults
Al Rabi K et al. Clin Lymphoma Myeloma Leuk, Oct 2024 - A high proportion of germline variants in pediatric chronic myeloid leukemia in pediatric chronic myeloid leukemia
Krumbhold M et al. Mol Cancer, Sept 2024 – open access publication - CAR-T cells for the treatment of pediatric chronic myeloid leukemia in repeatedly relapsed lymphoid blast crisis
Kramp LJ et al. Ann Hematol, Sept 2024 (epub ahead of print) – open access publication - Low-level BCR::ABL1 transcript at diagnosis in childhood leukemia: A 10-year single institution study
Cain LE et al. Genes Chromosomes Cancer, Sept 2024 - Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf) – Case No. 1: A Boy Presenting With Priapism and Loss of Vision
Roy Moulik et al. Case Rep Oncol Med, July 2024 – open access publication - Chronic myeloid leukemia in adolescents and young adults: Clinicopathological variables and outcomes
Abdulla MA et al. Oncology, July 2024 (epub ahead of print) – open access publication - Impact of tyrosine kinase inhibitors (TKIs) on growth in children and adolescents with chronic myeloid leukemia: A systematic review
Katsarou D et al. Curr Pharm Des, July 2024 (epub ahead of print) - Challenges in management of pediatric chronic myeloid leukemia (pCML) in the low-middle income countries (LMIC's): Insights from an International CML Foundation (iCMLf) Multi-National survey
Roy Moulik N et al. Pediatr Hematol Oncol, May 2024
Search here for more publications on pediatric CML