Please see below for a selection of interesting articles on pediatric CML in peer-reviewed journals.
We are delighted to share the second case review in our series dedicated to the treatment of pediatric CML (pCML) in low and middle-income countries (LMICs) that highlights a challenging case from Brazil. Experts discuss treatment discontinuation in a child with CML who has not achieved a sustained deep molecular response.
Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 2: Treatment-Free Remission After 9 Years of Imatinib Treatment Without Prior Achievement of Sustained Deep Molecular Response.
Michalowski, MB et al. Case Reports in Oncological Medicine, March 2025 – open access publication
This series of pediatric CML case reviews aims to provide a comprehensive discussion of challenging pCML cases from various perspectives to enhance knowledge and improve patient outcomes.
Other latest publications include:
- How I treat chronic myeloid leukemia in children and adolescents
Chen J et al. Blood, January 2026 - Predictors of response to imatinib therapy and long-term outcomes in pediatric and adolescent patients with chronic myeloid leukemia
Saha S et al. Cancer Rep (Hobokken), January 2026 – open access publication - Safety profiles of dasatinib in pediatric patients: a real-world pharmacovigilance assessment based on the FAERS database
Yang Y et al. Jpn J Clin Oncol, January 2026 – open access publication - Real-world efficacy and adverse events of frontline nilotinib in pediatric chronic myeloid leukemia in chronic phase: A prospective multicenter study from SCCCG(Plus)-CML 2023
Fan Z et al. Cancer, December 2025 – open access publication - Catch-up growth after switch to asciminib in a twin with chronic myeloid leukemia
Sembill S et al. Lancet, November 2025 (epub ahead of print) – open access publication - An old leukaemia in young patients – Genetic characteristics of paediatric chronic myeloid leukemia – Review
Metzler M et al. Br J Haematol, Sept 2025 (epub ahead of print) - Children with chronic phase chronic myeloid leukemia: Characteristics and outcomes from the International Registry of Childhood CML
Millot F et al. Haematologica, October 2025 (epub ahead of print) – open access publication - Pediatric chronic myeloid leukemia: A decade of clinical experience at the NBL specialized hospital for children
Bourusky M et al. Leuk Res Rep, October 2025 – open access publication - Safety profiles of dasatinib in pediatric patients: A real-world pharmacovigilance assessment based on the FAERS database
Yang Y et al. Jp J Clin Oncol, October 2025 (epub ahead of print)
– open access publication - A cross-sectional analysis of the global burden of childhood leukemia from 1990-2021
Wang P et al. J Cancer Res Clin Oncol, October 2025 – open access publication - Complications at diagnosis of pediatric chronic myeloid leukemia in chronic phase
Roy Moulik N et al. Pediatr Blood Cancer, August 2025 (epub ahead of print)
– open access publication - NAMP-mediated deacetylation of HSLS1 protein promotes clonogenic growth of pediatric CML cells
Samareh B et al. Exp Hematol, August 2025 – open access publication - Somatic mutations and outcomes in chronic myeloid leukemia adolescent and young adults compared to children, adults, and BCR::ABL1-positive acute lymphoblastic leukemia
Krizkova J et al. Leukemia, July 2025 – open access publication - Long-term endocrine outcomes and quality of life in pediatric and young chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy: A prospective study from India
Mohan R et al. Front Oncol, July 2025 – open access publication - Rare manifestations of pediatric chronic myeloid leukemia: A case report on priapism and a literature review
Budair R et al. Front Oncol, June 2025 – open access publication - Quality of life and adherence to tyrosine kinase inhibitors among pediatric, adolescent, and young adult chronic myeloid leukemia patients: A systematic Review
Werk RS et al. Pediatr Blood Cancer, June 2025 – open access publication - Survival of European children, adolescents, and young adults diagnosed with haematological malignancies in the period 2000 – 2013: Results from EUROCARE-6, a population based study
Trama A et al. Eur J Cancer, June 2025 – open access publication - Genomic variant profiling in blast-phase paediatric chronic myeloid leukemia: Predisposing and driving alterations
Behrens YL et al. Br J Haematol, May 2025 (epub ahead of print) – open access publication - Allogeneic hematopoietic stem cell transplantation in pediatric and young adult patients with chronic myeloid leukemia in tyrosine kinase inhibitor er: A study of the Korean Blood and Marrow Transplantation Registry
Ju HY et al. Cancer Res Treat, May 2025 (epub ahead of print) – open access publication - Management of children and adolescents with chronic myeloid leukemia in chronic-phase: International pediatric chronic myeloid leukemia expert panel recommendations
Millot F et al. Leukemia, March 2025 (epub ahead of print)
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