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CML Expert Opinions

Tiong Ong 1

Mechanisms of disease progression in chronic myeloid leukemia
Dr. S. Tiong Ong, Duke-NUS Medical School Singapore &
Division of Hematologic Malignancies and Cellular Therapy, Duke University Medical Center, NC, USA

Learning goals:

  • Understand that BP progression is characterized by a common, or 'core' transcriptome
  • Understand that polycomb complex (PCR-)-driven processes contribute to the 'core' transcriptome
  • Appreciate that a PCR-based model of CML progression identifies putative CP biomarkers
    and therapeutic strategies

This talk was first presented during the  Scientific Working Group Session – ELN-EHA-SWG for CML: 'Understanding the pathogenesis of CML' at EHA 2022