As part of our monthly news service we would like to make you aware of the CML publications of the month. From the many papers published every month Professor Timothy Hughes has selected topical, interesting papers for your perusal that also include interesting publications from low- and middle-income countries.
Read Professor Hughes' CML publications of the month: April 2024
Clinical CML papers
- Long-term outcomes after upfront second-generation tyrosine kinase inhibitors for chronic myeloid leukemia: managing intolerance and resistance
Claudiani S et al. Leukemia, April 2024 – open access publication - Mismatched related donor allogeneic haematopoietic cell transplantation compared to other donor types for Ph+ chronic myeloid leukemia: A retrospective analysis from the Chronic Malignancies Working Party of the EBMT
Onida F et al. Br J Haematol, April 2024 (epub ahead of print) – open access publication
- Effect of tyrosine kinase inhibitors on male fertility in patients with chronic phase chronic myeloid leukemia
Nesr G et al. Leuk Lymphoma, April 2024 (epub ahead of print) – open access publication - Combination therapies with ponatinib and asciminib in a preclinical model of chronic myeloid leukemia blast crisis with compound mutations
Curik N et al. Leukemia, April 2024 (epub ahead of print) – open access publication - Changes in chronic myeloid leukemia treatment modalities and outcomes after introduction of second-generation tyrosine kinase inhibitors as first-line therapy:
a multi-institutional retrospective study by the CML Cooperative Study Group
Iriyama N et al. Int J Hematol, April 2024 (epub ahead of print) - Combination of dasatinib and venetoclax in newly diagnosed chronic phase chronic myeloid leukemia
Jabbour E et al. Cancer, April 2024 (epub ahead of print) - The Mozart effect in chronic myeloid leukemia
Stentoft J et al. Br J Haematol, April 2024 – open access publication - Hepatotoxicity as dose-limiting toxicity of the combination of bosutinib and atezolizumab in patients with chronic myeloid leukemia. Results of the ZEROLMC study
Pérez-Lamas L et al. Ann Hematol, April 2024 (epub ahead of print) - Effect of tyrosine kinase inhibitor therapy on estimated glomerular filtration rate in patients with chronic myeloid leukemia
Sönmez Ö et al. Clin Lymphoma Myeloma Leuk, April 2024 - Does presence of complex translocations involving BCR::ABL1 in chronic myeloid leukemia affect the response rate to tyrosine kinase inhibitors? A systematic review of the literature - Review
Sharma D et al. Ann Diagn Pathol, April 2024 (epub ahead of print) - Oral arsenic plus imatinib versus imatinib solely for newly diagnosed chronic myeloid leukemia: a randomized phase 3 trial with 5-year outcomes
Tian J et al. J Cancer Res Clin Oncol, April 2024 – open access publication - Prediction of deep molecular response in chronic myeloid leukemia using supervised machine learning models
Zad Z et al. Leuk Res, April 2024 (epub ahead of print) - Prognostic impact of bone marrow fibrosis and effects of tyrosine kinase inhibitors on bone marrow fibrosis in chronic myeloid leukemia
Pepeler MS et al. Clin Lymphoma Myeloma Leuk, April 2024 - The depth of molecular response in patients with chronic myeloid leukemia correlates with changes in humoral immunity
Janowski M et al. J Clin Med, April 2024 – open access publication
- Incidence of pleural effusion with dasatinib and the effect of switching therapy to a different TKI in patients with chronic phase chronic myeloid leukemia
Jain AG et al. Ann Hematol, April 2024 (epub ahead of print) – open access publication
Scientific CML papers
- BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib
Leyte-Vidal A et al. Blood, April 2024 (epub ahead of print) - Unveiling IL6R and MYC as targeting biomarkers in imatinib-resistant CML through advanced non-invasive Apoptosis Detection Sensor Version 2 Detection
Lee CH et al. Cells, April 2024 – open access publication - Characterization of asciminib-resistant Philadelphia chromosome-positive cells
Okabe S et al. World J Oncol, April 2024 – open access publication - Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
Adnan-Awad S et al. Cell Rep Med, April 2024 (epub ahead of print) – open access publication
- High level of CD8+ PD-1+ cells in patients with chronic myeloid leukemia who experienced loss of MMR after imatinib discontinuation
Kwasnik P et al. Cells, April 2024 – open access publication
LMIC CML papers
- Hematological, clinical, cytogenetic and molecular profiles of confirmed chronic myeloid leukemia patients at presentation of a tertiary care teaching hospital in Addis Ababa, Ethiopia: a cross-sectional study
Urgessa F et al. BMC Cancer, April 2024 – open access publication
- Cytogenetic and epidemiological profile of chronic myeloid leukemia in Morocco
Benchikh S et al. Ann Hematol, April 2024 (epub ahead of print) - Mutation analysis of BCR-ABL1 kinase domain in chronic myeloid leukemia patients with tyrosine kinase inhibitor resistance: a Malaysian Cohort Study
Seman ZA et al. BMC Res Notes, April 2024 – open access publication