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Jane Apperley, MBChB, MD, FRCP, FRCPath
Professor of Medicine Chair, Department of Haematology Hammersmith Hospital
Imperial College, London (UK)
Professor Jane Apperley is the Chair of the Department of Haematology at the Imperial College and the Chief of Service for Clinical Haematology at the Imperial College Healthcare NHS Trust in London, England. Jane Apperley served as the President of both the European Group of Blood and Marrow Transplantation and the British Society of Blood and Marrow Transplantation. She also serves on the Advisory Board of the Centre for International Blood and Marrow Transplant Research.
She qualified in Medicine from the University of Birmingham and after initial specialization in internal medicine she completed specialist training in hematology in Birmingham, London, Cambridge and Boston.
Her particular interests are the biology and management of CML, which has led to an extensive experience in stem cell transplantation and to the use of signal transduction inhibitors. Her group at the Hammersmith Hospital site has extensive experience in the use of the first- and second-generation TKI’s, particularly in the areas of molecular monitoring and mechanisms of drug resistance. She has a long-standing interest in the ways in which hematologic diseases and their treatment impact fertility, pregnancy, and fetal outcome.
Jerald P. Radich, MD
Jerald P. Radich, M.D., is a Member of the Clinical Research Division at the Fred Hutchinson Cancer Research Center and is Professor of Medicine at the University of Washington. He is the Medical Director of the Research Trials Office at the FHCRC, the co-chair of Leukemia Biology for the Southwest Oncology Group, and is the co-chair of the NCI/Cooperartive Group Leukemia Steering Committee. He belongs to the National Cancer Care Network and EuroLeukemiaNet CML committees. Dr. Radich’s main research interest concerns the genetics of leukemia, and the use of and development of modern molecular biology techniques towards early detection of leukemia.
Jiri Mayer
Prof. Dr. Jiri Mayer
Prof. Dr. Jiri Mayer (jmayer@fnbrno.cz), is Deputy Head of the Dept. of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic, and now also the Dean of the Medical Faculty, Masaryk University Brno, Czech Republic.
He graduated in 1985 at Brno. After training in general internal medicine during 1985-1990, he started to work at the specialized hematology dept., where he has been working up to now. His certified qualifications are internal medicine, hematology, and oncology. Since 2001, he has been a Professor at the Medical School, Masaryk´s University, Brno, Czech Republic. His scientific experience comprises:
- Internal medicine, intensive care medicine
- Hemorheology
- Supportive care in hematology/oncology, especially diagnostics and treatment of infection in immunocompromissed patients
- Autologous and allogeneic bone marrow transplantation
- Peripheral blood stem cell transplantation
- Adult stem cell therapy
- Diagnostic and therapy of lymphomas and leukemias (especially CML)
In 1990, he visited Cancer Research Institute in Berlin, Germany, and in 1996, Royal Marsden Hospital, Leukaemia/Myeloma Unit, London, UK.
He is a member of European Group for Blood and Marrow Transplantation, American Society of Hematology, International Society for Experimental Hematology, European Haematology Association, and American Society for Blood and Marrow Transplantation.
He is also founding member and now chairman of the CzEch Leukemia Study Group for Life, CELL (http://leukemia-cell.org).
He has been the principal investigator of many trials since 1995, in the fields of lymphomas and leukemias. He has published more than 300 papers, abstracts, and lectures.
John Goldman
Professor John M Goldman DM, FRCP,FRCPath, FMedSci
Senior Research Investigator
Division of Investigative Science
Imperial College London, UK
Professor John M. Goldman has a long standing interest in the biology and therapy of chronic myeloid leukemia (CML). He was until 2004 Chairman of the Department of Haematology at Imperial College London, Director of the Leukaemia Research Fund Centre for Adult Leukaemia and Clinical Director of the Haematology Department at the Hammersmith Hospitals NHS Trust. Thereafter he took up a 2-year appointment as Fogarty Scholar at the National Institutes of Health in Bethesda USA. He is now active as Emeritus Professor of Haematology at Imperial College London and Medical Director of the Anthony Nolan Trust. He is editor of Bone Marrow Transplantation, a former editor of The Haematology Journal, and an associate editor of the European Journal of Haematology. He is also an editorial board member of numerous other journals and, during the course of his career, has published over 800 papers in peer-reviewed journals. As well as being the founding president of the British Society for Blood and Marrow Transplantation, he is a former president of the International Society for Experimental Hematology, the European Group for Blood and Marrow Transplantation and the European Hematology Association.
Professor Goldman was the first to autograft patients with CML using peripheral blood stem cells and started allogeneic stem cell transplant for CML in 1980. He pioneered the use of unrelated donors for transplanting CML patients and developed PCR technology for monitoring residual disease. He confirmed the preclinical efficacy of the original tyrosine kinase inhibitor (STI571, now imatinib) in 1997 and first used it in the clinic in 1999. Thereafter he has been involved in development of second generation TKIs, notably dasatinib and nilotinib.
Jorge Cortes, MD
Professor of Medicine
Chief, CML Section
Department of Leukemia
The University of Texas MD Anderson Cancer Center
Houston, Texas
Jorge Cortes, MD, is deputy chair and professor of medicine in the Department of Leukemia at The University of Texas MD Anderson Cancer Center, Houston Texas where he directs the CML Program. Dr. Cortes received his medical degree in 1986 from the Universidad Nacional Autonoma de Mexico, Mexico City, and has been at MD Anderson Cancer Center since 1991. Dr. Cortes, whose clinical interest focus on new drug development and the management of patients with myelodysplastic syndromes, acute and chronic leukemias, and myeloproliferative disorders has authored over 400 peer-reviewed medical publications. He has received numerous awards including the Faculty Scholar Award from MD Anderson Cancer Center in 2003, the Annual Celgene Young Investigator Achievement Award for Clinical Research in Hematology in 2005, The Dr. John J. Kenny Award from The Leukemia & Lymphoma Society in 2006, the Service to Mankind Award from The Leukemia & Lymphoma Society in 2007, and the Otis W. and Pearl L. Walters Faculty Achievement Award in Clinical Research from MD Anderson Cancer Center in 2007. Dr. Cortes is chief editor of Current Hematological Malignancies Reports and Clinical Leukemia and serves in the Editorial Board of the Journal of Clinical Oncology, Leukemia, Clinical Cancer Research, Leukemia and Lymphoma and the American Journal of Hematology.
Francisco Cervantes
Francisco Cervantes is senior consultant at the Hematology Department of the Hospital Clínic, in Barcelona, Spain, and associate professor at the University of Barcelona. His main scientific interest is the study of chronic myeloid leukemia (CML) and the Ph-negative chronic myeloproliferative neoplasms (MPNs), mainly their natural history, prognosis, biology, and treatment. As a result of the activity in this field, he has published more than 190 articles in peer-review international journals, including the New England Journal of Medicine, Blood, Journal of Clinical Oncology, Leukemia, British Journal of Haematology, Experimental Hematology, Haematologica, Cancer, Oncogene, Seminars in Oncology, and the European Journal of Haematology. In the CML field,Dr. Cervantes contributed to the elaboration of Sokal’s score, is a coauthor of the publications of the IRIS study, which established imatinib as first-line treatment for CML, has participated in the introduction of the second-generation tyrosine kinase inhibitors for patients resistant to imatinib, as well as in the authorship of the European LeukemiaNet recommendations for the treatment of CML. His more recent contributions in the field of the MPNs have been the elaboration of the new prognostic classification of primary myelofibrosis on behalf of the International Working Group for Myelofibrosis Research and Treatment, as well as several studies on the role of leukocyte and platelet activation in the thrombosis of MPN patients. At local level, he is the national coordinator of the CML studies within the collaborative PETHEMA Spanish group. Dr Cervantes is a member of the American Society of Hematology, the European Hematology Association, the International Working Group for Myeloproliferative Neoplasms Research and Treatment, the European Leukemianet, and the Spanish Society of Hematology.
Jose Luis Lopez
José Luis Lopez, MD
Caracas, Venezuela
Dr. Lopez is a Professor of Hematology and Internal Medicine at the "Universidad Central de Venezuela". Head of the Department of Hematology Clinics at the Banco Municipal de Sangre in Caracas, starting his work in this Institution in Hemato-Oncology Clinic at 1991 and developed the Molecular Dx Laboratory in 1992.
He occupied the Secretary position (2001-2003) at Venezuelan Society of Hematology and was a Founder Member of the National Transplant Organization of Venezuela.
Dr Lopez is an active member in the Investigation Department of his Medical Center and have been interested in Clinical Research and Molecular Genetic of Chronic Leukemias, collaborating like an Investigator Overseas in NCI-Cancer Therapy Evaluation Program (1995-1997).
