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Assuming the cml is under good control, continue the imatinib. Remember that IM and other tKIs have little effect on normal stem cells. I have treated several cml patients with breast, lung, lymphoma, colon and in only one case of bladder, did the TKI have to be held.
GCSF unlikely to be necessary because of the CML, but little evidence that it impacts CML
Dear colleagues,
I completely agree with the tactics proposed by Professor Gianantonio Rosti and Dr. Valentin Garcia Gutierrez/ Currently, no G-CSF assignment is required. Combined therapy with imatinib and chemotherapy is usually well tolerated by patients
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