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Overview of iCMLf programs

The iCMLf is committed to improving the outcomes for CML patients globally. The aim of the iCMLf is to foster and coordinate global clinical and research collaborations and to improve clinical practice and disease monitoring in CML. To achieve these goals the foundation coordinates numerous programs that mainly focus on education and access to treatment and diagnosis, primarily for emerging regions. The iCMLf current activities relate to three core areas:

  • Intensive educational programs for physicians unable to easily access international meetings
  • Increasing access to CML diagnostics to improve patient outcomes
  • Online education to spread best practice

The Emerging Regions Support and Partnership (ERSAP) Programs focus on areas with limited resources to manage CML and this is the primary focus of the Foundation. 

Educational programs

The iCMLf Conversations

The iCMLf hosts regular live webinars with renowned experts discussing various topics in CML management. The series of expert talks also includes webinars on CML and COVID-19 in English and other languages. All past conversations are available to view on-demand on the iCMLf website.

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Clinical Case Discussion Forum (international)

This discussion forum on the iCMLf website aims to share and enhance best practice management of CML. Clinicians can post difficult or interesting CML patient cases for discussion. Each clinical case is forwarded to the iCMLf expert clinical panel for a brief independent response. The topic is then opened for discussion and comment in the online forum.
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Access to CML Diagnostics

The Diagnosis and Testing Program (LMICs)

The iCMLf Diagnosis and Testing Program provides diagnostic testing and ultimately disease monitoring for CML patients in emerging economic countries where this is limited or not currently available. Through the Program the iCMLf will build capacity at a local level to bring high quality testing to the patient, or to develop a low cost strategy for sending patient samples to a central referral laboratory for testing.

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Finding a cure for CML

The iCMLf Genomic Alliance

The iCMLf has established the iCMLf Genomics Alliance with the aim to harness the wealth of genomic information that is generated in local CML research projects by building a platform to facilitate data assimilation and sample exchanges. Combining many data sets and facilitating global collaboration studies will enable us to better understand the relationship between genomic aberrations and patient outcomes.

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The iCMLf TFR Alliance

The iCMLf also formed a second Alliance under the banner of CURE - the iCMLf Treatment-Free-Remission (TFR) Alliance to establish a global registry for TFR cases. The purpose of the global registry is to develop and validate predictors of TFR success, look at other aspects of TFR outcomes, and (critically) facilitate exchange of clinically annotated samples from registry patients to further our understanding about the biological and molecular features of TFR.

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