The inaugural iCMLf Forum: Saudi Arabia - Progress and Practice in CML brought together 43 physicians from across the Kingdom and beyond for a full day of evidence-based updates, debate, and clinical discussion in Riyadh. As our first iCMLf Forum delivered outside the United States, this meeting on November 1st 2025 marked an important milestone in strengthening global collaboration around CML management.
Led by Professors Jorge Cortes, Tim Hughes and Giuseppe Saglio, alongside an exceptional Saudi faculty including Professor Naeem Chaudhri, Dr Mohammed Almakadi, Dr Marwan Shaheen and Dr Binyam Usman, the Forum explored the latest science shaping CML management in 2025.
October 2025 - We're bringing you highlights from the recent ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy with a summary of selected scientific sessions.
Chair: Mary Scott (Glasgow)
This session explored new insights into leukemic stem cell biology, persistence, and the bone marrow microenvironment in CML. The speakers presented novel models and molecular mechanisms driving stem cell survival and relapse, highlighting inflammatory, metabolic, and stromal interactions shaping disease behaviour and treatment-free remission (TFR) potential.

October 2025 - Thank you to everyone who joined the 2025 John Goldman Run Run, held during the recent ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy in Estoril.
This year’s Run was a huge success!
More than 50 participants set off before sunrise for a 5-km run along the scenic seaside route, proudly wearing this year’s purple Fun Run charity t-shirts.
Together, we raised $2,900 – more funds than ever before – in support of the iCMLf programs that improve access to CML education and care in low- and middle-income countries.
A heartfelt thank you to all our individual supporters.
Recap of ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy on October 22nd at 14.00October 2025 - Here’s a quick reminder about next week’s iCMLf Conversation – ‘Highlights from ESHCML2025’, taking place on Wednesday, October 22nd.
📅 Date: Wednesday, October 22nd
🕑 Time: 14:00 CEST
🖥️ Format: Live webinar on Zoom
Join Professors Daniela Krause and Jorge Cortes - co-chairs of the ESH–iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy – as they share their personal take on the most exciting biological and clinical highlights from the meeting.

The International CML Foundation (iCMLf) is proud to share its 2024–25 Annual Report, marking a year of global collaboration and tangible progress in CML care, research, and education.
Over the past year, iCMLf programs reached hundreds of thousands of people in 139 countries, with nearly two-thirds of engagement coming from low- and middle-income regions. This global reach reflects our ongoing commitment to equity in CML care and access to expert knowledge for all.
September 2025 - We invite you to join the next iCMLf Conversation on Wednesday, October 22nd, at 14:00 CEST. We will take an in-depth look at the latest CML research and data presented at the ESH-iCMLf 27th Annual John Goldman Conference on CML: Biology and Therapy.
Whether or not you will join us in Estoril on October 10–12, this webinar offers a unique opportunity to hear the key highlights from the conference. Co-chairs Professors Daniela Krause and Jorge Cortes will share their expert perspectives on the most important data presented, discuss its implications for the field, and offer their thoughts on what lies ahead in CML biology and therapy.
This is your chance to gain a concise expert overview of cutting-edge science, benefit from the co-chairs’ insights into both established and emerging trends and put your questions directly to them during the live discussion. Don’t miss the opportunity to engage with global leaders in CML research and explore what’s next for patients and clinicians worldwide.